The combination of A-966492 and Topotecan for effective radiosensitization on glioblastoma spheroids.

Koosha, Fereshteh; Neshasteh-Riz, Ali; Takavar, Abbas; Eyvazzadeh, Nazila; Mazaheri, Zohreh; Eynali, Samira; Mousavi, Mehdi

Koosha, Fereshteh; Neshasteh-Riz, Ali; Takavar, Abbas; Eyvazzadeh, Nazila; Mazaheri, Zohreh; Eynali, Samira; Mousavi, Mehdi.

Afiliação

Koosha F; Department of Medical Physics and Biomedical Engineering, Faculty of Medicine, Tehran University of Medical Sciences, Tehran, Iran; Radiation Biology Research Center, Iran University of Medical Sciences, Tehran, Iran.
Neshasteh-Riz A; Radiation Biology Research Center, Iran University of Medical Sciences, Tehran, Iran; Department of Radiation Sciences, School of Para Medicine, Iran University of Medical Sciences, Tehran, Iran. Electronic address: neshastehriz@yahoo.com.
Takavar A; Department of Medical Physics and Biomedical Engineering, Faculty of Medicine, Tehran University of Medical Sciences, Tehran, Iran. Electronic address: Takavar@sina.tums.ac.ir.
Eyvazzadeh N; Radiation Research Center, Faculty of Para Medicine, AJA University of Medical Sciences, Tehran, Iran.
Mazaheri Z; Department of Anatomical Sciences, Medical Sciences Faculty, Tarbiat Modares University, Tehran, Iran.
Eynali S; Radiation Biology Research Center, Iran University of Medical Sciences, Tehran, Iran.
Mousavi M; School of Medicine, Jiroft University of Medical Sciences, Jiroft, Iran.

Biochem Biophys Res Commun ; 491(4): 1092-1097, 2017 09 30.

Article em En | MEDLINE | ID: mdl-28797568

Assuntos

Benzimidazóis/farmacologia; Glioblastoma/tratamento farmacológico; Esferoides Celulares/efeitos dos fármacos; Inibidores da Topoisomerase I/farmacologia; Topotecan/farmacologia; Benzimidazóis/administração & dosagem; Linhagem Celular Tumoral; DNA Topoisomerases Tipo I/metabolismo; Humanos; Tolerância a Radiação/efeitos dos fármacos; Relação Estrutura-Atividade; Inibidores da Topoisomerase I/administração & dosagem; Topotecan/administração & dosagem; Raios X

Palavras-chave

Glioblastoma; PARP inhibitor; Radiosensitivity; Topoisomerase I inhibitor; Topotecan

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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Benzimidazóis / Glioblastoma / Esferoides Celulares / Topotecan / Inibidores da Topoisomerase I Limite: Humans Idioma: En Revista: Biochem Biophys Res Commun Ano de publicação: 2017 Tipo de documento: Article País de afiliação: Irã

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