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Design, synthesis and biological evaluation of novel coumarin-N-benzyl pyridinium hybrids as multi-target agents for the treatment of Alzheimer's disease.
Lan, Jin-Shuai; Ding, Yue; Liu, Yun; Kang, Ping; Hou, Jian-Wei; Zhang, Xin-Yu; Xie, Sai-Sai; Zhang, Tong.
Afiliação
  • Lan JS; Experiment Center of Teaching & Learning, Shanghai University of Traditional Chinese Medicine, Shanghai 201203, China.
  • Ding Y; Experiment Center of Teaching & Learning, Shanghai University of Traditional Chinese Medicine, Shanghai 201203, China.
  • Liu Y; Experiment Center of Teaching & Learning, Shanghai University of Traditional Chinese Medicine, Shanghai 201203, China.
  • Kang P; Experiment Center of Teaching & Learning, Shanghai University of Traditional Chinese Medicine, Shanghai 201203, China.
  • Hou JW; Experiment Center of Teaching & Learning, Shanghai University of Traditional Chinese Medicine, Shanghai 201203, China.
  • Zhang XY; Experiment Center of Teaching & Learning, Shanghai University of Traditional Chinese Medicine, Shanghai 201203, China.
  • Xie SS; National Pharmaceutical Engineering Center for Solid Preparation in Chinese Herbal Medicine, Jiangxi University of Traditional Chinese Medicine, Nanchang 330006, China. Electronic address: xiesaisainanchang@hotmail.com.
  • Zhang T; School of Pharmacy, Shanghai University of Traditional Chinese Medicine, Shanghai 201203, China. Electronic address: zhangtongshutcm@hotmail.com.
Eur J Med Chem ; 139: 48-59, 2017 Oct 20.
Article em En | MEDLINE | ID: mdl-28797883
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Compostos de Piridínio / Desenho de Fármacos / Inibidores da Colinesterase / Cumarínicos / Doença de Alzheimer / Inibidores da Monoaminoxidase Limite: Animals / Humans Idioma: En Revista: Eur J Med Chem Ano de publicação: 2017 Tipo de documento: Article País de afiliação: China
Texto completo
Imprimir
XML
PubMed Links
Buscar no Google

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Compostos de Piridínio / Desenho de Fármacos / Inibidores da Colinesterase / Cumarínicos / Doença de Alzheimer / Inibidores da Monoaminoxidase Limite: Animals / Humans Idioma: En Revista: Eur J Med Chem Ano de publicação: 2017 Tipo de documento: Article País de afiliação: China