Inhibition of H3K4 demethylation induces autophagy in cancer cell lines.

Wang, Zhen; Long, Qiao-Yun; Chen, Lin; Fan, Jia-Dong; Wang, Zhao-Ning; Li, Lian-Yun; Wu, Min; Chen, Xuefeng

Wang, Zhen; Long, Qiao-Yun; Chen, Lin; Fan, Jia-Dong; Wang, Zhao-Ning; Li, Lian-Yun; Wu, Min; Chen, Xuefeng.

Afiliação

Wang Z; Hubei Key Laboratory of Cell Homeostasis, China; Hubei Key Laboratory of Developmentally Originated Disease, China; Department of Biochemistry and Molecular Biology, China.
Long QY; Hubei Key Laboratory of Cell Homeostasis, China; Hubei Key Laboratory of Developmentally Originated Disease, China; Department of Biochemistry and Molecular Biology, China.
Chen L; Hubei Key Laboratory of Cell Homeostasis, China; Hubei Key Laboratory of Developmentally Originated Disease, China; Department of Biochemistry and Molecular Biology, China.
Fan JD; Hubei Key Laboratory of Cell Homeostasis, China; Department of Biochemistry and Molecular Biology, China.
Wang ZN; Hubei Key Laboratory of Cell Homeostasis, China; Department of Biochemistry and Molecular Biology, China.
Li LY; Hubei Key Laboratory of Cell Homeostasis, China; Hubei Key Laboratory of Developmentally Originated Disease, China; Department of Biochemistry and Molecular Biology, China. Electronic address: lilianyun@whu.edu.cn.
Wu M; Hubei Key Laboratory of Cell Homeostasis, China; Hubei Key Laboratory of Developmentally Originated Disease, China; Department of Biochemistry and Molecular Biology, China. Electronic address: wumin@whu.edu.cn.
Chen X; Hubei Key Laboratory of Cell Homeostasis, China; Department of Genetics, College of Life Sciences, Wuhan University, Wuhan, Hubei 430072, China. Electronic address: xfchen@whu.edu.cn.

Biochim Biophys Acta Mol Cell Res ; 1864(12): 2428-2437, 2017 Dec.

Article em En | MEDLINE | ID: mdl-28800922

Assuntos

Autofagia/genética; Histona Desmetilases/genética; Proteínas Associadas aos Microtúbulos/genética; Proteína Sequestossoma-1/metabolismo; Animais; Autofagossomos/efeitos dos fármacos; Autofagossomos/metabolismo; Autofagia/efeitos dos fármacos; Proteína Homóloga à Proteína-1 Relacionada à Autofagia/genética; Proteína Beclina-1/genética; Epigênese Genética/genética; Regulação da Expressão Gênica/efeitos dos fármacos; Células HCT116; Histona Desmetilases/antagonistas & inibidores; Histona Desmetilases/metabolismo; Humanos; Peptídeos e Proteínas de Sinalização Intracelular/genética; Proteínas Associadas aos Microtúbulos/metabolismo; Piperazinas/farmacologia; Proteína Sequestossoma-1/genética

Palavras-chave

2-PCPA; Autophagy; Epigenetic inhibitors; GSK-LSD1; KDM1A/LSD1

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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Autofagia / Histona Desmetilases / Proteína Sequestossoma-1 / Proteínas Associadas aos Microtúbulos Limite: Animals / Humans Idioma: En Revista: Biochim Biophys Acta Mol Cell Res Ano de publicação: 2017 Tipo de documento: Article País de afiliação: China

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