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PI-273, a Substrate-Competitive, Specific Small-Molecule Inhibitor of PI4KIIα, Inhibits the Growth of Breast Cancer Cells.
Li, Jiangmei; Gao, Zhen; Zhao, Dan; Zhang, Lunfeng; Qiao, Xinhua; Zhao, Yingying; Ding, Hong; Zhang, Panpan; Lu, Junyan; Liu, Jia; Jiang, Hualiang; Luo, Cheng; Chen, Chang.
Afiliação
  • Li J; National Laboratory of Biomacromolecules, CAS Center for Excellence in Biomacromolecules, Institute of Biophysics, Chinese Academy of Sciences, Chaoyang District, Beijing, China.
  • Gao Z; Shanghai Institute for Advanced Immunochemical Studies, ShanghaiTech University, Shanghai, China.
  • Zhao D; National Laboratory of Biomacromolecules, CAS Center for Excellence in Biomacromolecules, Institute of Biophysics, Chinese Academy of Sciences, Chaoyang District, Beijing, China.
  • Zhang L; University of Chinese Academy of Sciences, Shijingshan District, Beijing, China.
  • Qiao X; University of Chinese Academy of Sciences, Shijingshan District, Beijing, China.
  • Zhao Y; Drug Discovery and Design Center, State Key Laboratory of Drug Research, Shanghai Institute of Materia Medica, Chinese Academy of Sciences, Shanghai, China.
  • Ding H; National Laboratory of Biomacromolecules, CAS Center for Excellence in Biomacromolecules, Institute of Biophysics, Chinese Academy of Sciences, Chaoyang District, Beijing, China.
  • Zhang P; University of Chinese Academy of Sciences, Shijingshan District, Beijing, China.
  • Lu J; National Laboratory of Biomacromolecules, CAS Center for Excellence in Biomacromolecules, Institute of Biophysics, Chinese Academy of Sciences, Chaoyang District, Beijing, China.
  • Liu J; University of Chinese Academy of Sciences, Shijingshan District, Beijing, China.
  • Jiang H; National Laboratory of Biomacromolecules, CAS Center for Excellence in Biomacromolecules, Institute of Biophysics, Chinese Academy of Sciences, Chaoyang District, Beijing, China.
  • Luo C; Shanghai Institute for Advanced Immunochemical Studies, ShanghaiTech University, Shanghai, China.
  • Chen C; Drug Discovery and Design Center, State Key Laboratory of Drug Research, Shanghai Institute of Materia Medica, Chinese Academy of Sciences, Shanghai, China.
Cancer Res ; 77(22): 6253-6266, 2017 11 15.
Article em En | MEDLINE | ID: mdl-28827373
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Tiofenos / Tioureia / Neoplasias da Mama / Fosfotransferases (Aceptor do Grupo Álcool) / Proliferação de Células / Inibidores Enzimáticos / Bibliotecas de Moléculas Pequenas Limite: Animals / Female / Humans / Male Idioma: En Revista: Cancer Res Ano de publicação: 2017 Tipo de documento: Article País de afiliação: China
Texto completo
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Tiofenos / Tioureia / Neoplasias da Mama / Fosfotransferases (Aceptor do Grupo Álcool) / Proliferação de Células / Inibidores Enzimáticos / Bibliotecas de Moléculas Pequenas Limite: Animals / Female / Humans / Male Idioma: En Revista: Cancer Res Ano de publicação: 2017 Tipo de documento: Article País de afiliação: China