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Pyrazole C-region analogues of 2-(3-fluoro-4-methylsulfonylaminophenyl)propanamides as potent TRPV1 antagonists.
Lee, Sunho; Kim, Changhoon; Ann, Jihyae; Thorat, Shivaji A; Kim, Eunhye; Park, Jongmi; Choi, Sun; Blumberg, Peter M; Frank-Foltyn, Robert; Bahrenberg, Gregor; Stockhausen, Hannelore; Christoph, Thomas; Lee, Jeewoo.
Afiliação
  • Lee S; Laboratory of Medicinal Chemistry, Research Institute of Pharmaceutical Sciences, College of Pharmacy, Seoul National University, Seoul 08826, Republic of Korea.
  • Kim C; Laboratory of Medicinal Chemistry, Research Institute of Pharmaceutical Sciences, College of Pharmacy, Seoul National University, Seoul 08826, Republic of Korea.
  • Ann J; Laboratory of Medicinal Chemistry, Research Institute of Pharmaceutical Sciences, College of Pharmacy, Seoul National University, Seoul 08826, Republic of Korea.
  • Thorat SA; Laboratory of Medicinal Chemistry, Research Institute of Pharmaceutical Sciences, College of Pharmacy, Seoul National University, Seoul 08826, Republic of Korea.
  • Kim E; National Leading Research Laboratory of Molecular Modeling & Drug Design, College of Pharmacy, Graduate School of Pharmaceutical Sciences, Ewha Womans University, Seoul 03760, Republic of Korea.
  • Park J; National Leading Research Laboratory of Molecular Modeling & Drug Design, College of Pharmacy, Graduate School of Pharmaceutical Sciences, Ewha Womans University, Seoul 03760, Republic of Korea.
  • Choi S; National Leading Research Laboratory of Molecular Modeling & Drug Design, College of Pharmacy, Graduate School of Pharmaceutical Sciences, Ewha Womans University, Seoul 03760, Republic of Korea.
  • Blumberg PM; Laboratory of Cancer Biology and Genetics, Center for Cancer Research, National Cancer Institute, NIH, Bethesda, MD 20892, USA.
  • Frank-Foltyn R; Grünenthal Innovation, Grünenthal GmbH, D-52078 Aachen, Germany.
  • Bahrenberg G; Grünenthal Innovation, Grünenthal GmbH, D-52078 Aachen, Germany.
  • Stockhausen H; Grünenthal Innovation, Grünenthal GmbH, D-52078 Aachen, Germany.
  • Christoph T; Grünenthal Innovation, Grünenthal GmbH, D-52078 Aachen, Germany.
  • Lee J; Laboratory of Medicinal Chemistry, Research Institute of Pharmaceutical Sciences, College of Pharmacy, Seoul National University, Seoul 08826, Republic of Korea. Electronic address: jeewoo@snu.ac.kr.
Bioorg Med Chem Lett ; 27(18): 4383-4388, 2017 09 15.
Article em En | MEDLINE | ID: mdl-28838698
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Fenilpropionatos / Pirazóis / Mesilatos / Canais de Cátion TRPV Limite: Humans Idioma: En Revista: Bioorg Med Chem Lett Assunto da revista: BIOQUIMICA / QUIMICA Ano de publicação: 2017 Tipo de documento: Article
Texto completo
Imprimir
XML
PubMed Links
Buscar no Google

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Fenilpropionatos / Pirazóis / Mesilatos / Canais de Cátion TRPV Limite: Humans Idioma: En Revista: Bioorg Med Chem Lett Assunto da revista: BIOQUIMICA / QUIMICA Ano de publicação: 2017 Tipo de documento: Article