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[Effect of rat intestinal flora in vitro on metabolites of acteoside].
Zhang, Wen-Xiu; Yang, Biao; Hu, Yu-Mei; Meng, Zhao-Qing; Huang, Wen-Zhe; Wang, Zhen-Zhong; Xiao, Wei.
Afiliação
  • Zhang WX; Jiangsu Kanion Pharmaceutical Co., Ltd., Lianyungang 222001, China.
  • Yang B; China Pharmaceutical University, Nanjing 210009, China.
  • Hu YM; Jiangsu Kanion Pharmaceutical Co., Ltd., Lianyungang 222001, China.
  • Meng ZQ; Jiangsu Kanion Pharmaceutical Co., Ltd., Lianyungang 222001, China.
  • Huang WZ; Jiangsu Kanion Pharmaceutical Co., Ltd., Lianyungang 222001, China.
  • Wang ZZ; Jiangsu Kanion Pharmaceutical Co., Ltd., Lianyungang 222001, China.
  • Xiao W; Jiangsu Kanion Pharmaceutical Co., Ltd., Lianyungang 222001, China.
Zhongguo Zhong Yao Za Zhi ; 41(8): 1541-1545, 2016 Apr.
Article em Zh | MEDLINE | ID: mdl-28884553
ABSTRACT
Acteoside was used for anaerobic incubation with rat intestinal flora in vitro. HPLC was used to detect the changes of acteoside at different incubation time points and HPLC-Q-TOF-MS was used to identify the metabolites of acteoside. The results showed that acteoside could be metabolized by rat intestinal flora in vitro and the metabolites were 3,4-dihydroxyphenyl acid, caffeic acid and 3-(3'-hydroxyphenyl) propionic acid.
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Fenóis / Microbioma Gastrointestinal / Glucosídeos Limite: Animals Idioma: Zh Revista: Zhongguo Zhong Yao Za Zhi Assunto da revista: FARMACOLOGIA / TERAPIAS COMPLEMENTARES Ano de publicação: 2016 Tipo de documento: Article País de afiliação: China
Texto completo
Imprimir
XML
PubMed Links
Buscar no Google

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Fenóis / Microbioma Gastrointestinal / Glucosídeos Limite: Animals Idioma: Zh Revista: Zhongguo Zhong Yao Za Zhi Assunto da revista: FARMACOLOGIA / TERAPIAS COMPLEMENTARES Ano de publicação: 2016 Tipo de documento: Article País de afiliação: China