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Alkoxycarbonate Ester Prodrugs of Preclinical Drug Candidate ELQ-300 for Prophylaxis and Treatment of Malaria.
Frueh, Lisa; Li, Yuexin; Mather, Michael W; Li, Qigui; Pou, Sovitj; Nilsen, Aaron; Winter, Rolf W; Forquer, Isaac P; Pershing, April M; Xie, Lisa H; Smilkstein, Martin J; Caridha, Diana; Koop, Dennis R; Campbell, Robert F; Sciotti, Richard J; Kreishman-Deitrick, Mara; Kelly, Jane X; Vesely, Brian; Vaidya, Akhil B; Riscoe, Michael K.
Afiliação
  • Frueh L; Experimental Chemotherapy Laboratory, VA Medical Center (Mail code RD-33), 3710 SW US Veterans Hospital Road, Portland, Oregon 97239, United States.
  • Li Y; Department of Molecular Microbiology and Immunology, Oregon Health and Science University , 3181 SW Sam Jackson Park Road, Portland, Oregon 97239, United States.
  • Mather MW; Experimental Chemotherapy Laboratory, VA Medical Center (Mail code RD-33), 3710 SW US Veterans Hospital Road, Portland, Oregon 97239, United States.
  • Li Q; Department of Microbiology and Immunology, Drexel University , 2900 W. Queen Lane, Philadelphia, Pennsylvania 19129, United States.
  • Pou S; Experimental Therapeutics Branch, Military Malaria Research Program (MMRP), Walter Reed Army Institute of Research , 503 Robert Grant Avenue, Silver Spring, Maryland 20910, United States.
  • Nilsen A; Department of Molecular Microbiology and Immunology, Oregon Health and Science University , 3181 SW Sam Jackson Park Road, Portland, Oregon 97239, United States.
  • Winter RW; Experimental Chemotherapy Laboratory, VA Medical Center (Mail code RD-33), 3710 SW US Veterans Hospital Road, Portland, Oregon 97239, United States.
  • Forquer IP; Experimental Chemotherapy Laboratory, VA Medical Center (Mail code RD-33), 3710 SW US Veterans Hospital Road, Portland, Oregon 97239, United States.
  • Pershing AM; Experimental Chemotherapy Laboratory, VA Medical Center (Mail code RD-33), 3710 SW US Veterans Hospital Road, Portland, Oregon 97239, United States.
  • Xie LH; Department of Microbiology and Immunology, Drexel University , 2900 W. Queen Lane, Philadelphia, Pennsylvania 19129, United States.
  • Smilkstein MJ; Experimental Therapeutics Branch, Military Malaria Research Program (MMRP), Walter Reed Army Institute of Research , 503 Robert Grant Avenue, Silver Spring, Maryland 20910, United States.
  • Caridha D; Experimental Chemotherapy Laboratory, VA Medical Center (Mail code RD-33), 3710 SW US Veterans Hospital Road, Portland, Oregon 97239, United States.
  • Koop DR; Experimental Therapeutics Branch, Military Malaria Research Program (MMRP), Walter Reed Army Institute of Research , 503 Robert Grant Avenue, Silver Spring, Maryland 20910, United States.
  • Campbell RF; Department of Physiology and Pharmacology, Oregon Health & Science University , 3181 S.W. Sam Jackson Park Road, Portland, Oregon 97239, United States.
  • Sciotti RJ; Experimental Therapeutics Branch, Military Malaria Research Program (MMRP), Walter Reed Army Institute of Research , 503 Robert Grant Avenue, Silver Spring, Maryland 20910, United States.
  • Kreishman-Deitrick M; Experimental Therapeutics Branch, Military Malaria Research Program (MMRP), Walter Reed Army Institute of Research , 503 Robert Grant Avenue, Silver Spring, Maryland 20910, United States.
  • Kelly JX; Experimental Therapeutics Branch, Military Malaria Research Program (MMRP), Walter Reed Army Institute of Research , 503 Robert Grant Avenue, Silver Spring, Maryland 20910, United States.
  • Vesely B; Experimental Chemotherapy Laboratory, VA Medical Center (Mail code RD-33), 3710 SW US Veterans Hospital Road, Portland, Oregon 97239, United States.
  • Vaidya AB; Experimental Therapeutics Branch, Military Malaria Research Program (MMRP), Walter Reed Army Institute of Research , 503 Robert Grant Avenue, Silver Spring, Maryland 20910, United States.
  • Riscoe MK; Department of Microbiology and Immunology, Drexel University , 2900 W. Queen Lane, Philadelphia, Pennsylvania 19129, United States.
ACS Infect Dis ; 3(10): 728-735, 2017 10 13.
Article em En | MEDLINE | ID: mdl-28927276
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Plasmodium falciparum / Pró-Fármacos / Quinolonas / Antimaláricos Limite: Animals Idioma: En Revista: ACS Infect Dis Ano de publicação: 2017 Tipo de documento: Article País de afiliação: Estados Unidos
Texto completo
Imprimir
XML
PubMed Links
Buscar no Google

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Plasmodium falciparum / Pró-Fármacos / Quinolonas / Antimaláricos Limite: Animals Idioma: En Revista: ACS Infect Dis Ano de publicação: 2017 Tipo de documento: Article País de afiliação: Estados Unidos