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Identifying therapeutic targets by combining transcriptional data with ordinal clinical measurements.
Pirhaji, Leila; Milani, Pamela; Dalin, Simona; Wassie, Brook T; Dunn, Denise E; Fenster, Robert J; Avila-Pacheco, Julian; Greengard, Paul; Clish, Clary B; Heiman, Myriam; Lo, Donald C; Fraenkel, Ernest.
Afiliação
  • Pirhaji L; Department of Biological Engineering, Massachusetts Institute of Technology, 77 Massachusetts Avenue, Cambridge, Massachusetts, 02139, USA.
  • Milani P; Department of Biological Engineering, Massachusetts Institute of Technology, 77 Massachusetts Avenue, Cambridge, Massachusetts, 02139, USA.
  • Dalin S; Department of Biological Engineering, Massachusetts Institute of Technology, 77 Massachusetts Avenue, Cambridge, Massachusetts, 02139, USA.
  • Wassie BT; Department of Biological Engineering, Massachusetts Institute of Technology, 77 Massachusetts Avenue, Cambridge, Massachusetts, 02139, USA.
  • Dunn DE; Center for Drug Discovery, Department of Neurobiology, Duke University Medical Center, 303 Research Drive, Durham, North Carolina, 27710, USA.
  • Fenster RJ; Picower Institute for Learning and Memory, 43 Vassar St, Cambridge, Massachusetts, 02139, USA.
  • Avila-Pacheco J; Laboratory of Cellular and Molecular Neuroscience, The Rockefeller University, 1230 York Ave, New York, New York, 10065, USA.
  • Greengard P; McLean Hospital, 115 Mill Street, Belmont, Massachusetts, 02478, USA.
  • Clish CB; Broad Institute, 415 Main St, Cambridge, Massachusetts, 02142, USA.
  • Heiman M; Laboratory of Cellular and Molecular Neuroscience, The Rockefeller University, 1230 York Ave, New York, New York, 10065, USA.
  • Lo DC; Broad Institute, 415 Main St, Cambridge, Massachusetts, 02142, USA.
  • Fraenkel E; Picower Institute for Learning and Memory, 43 Vassar St, Cambridge, Massachusetts, 02139, USA.
Nat Commun ; 8(1): 623, 2017 09 20.
Article em En | MEDLINE | ID: mdl-28931805
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Doença de Huntington / Aldeído Liases / Células-Tronco Neurais Tipo de estudo: Etiology_studies / Incidence_studies / Observational_studies / Prognostic_studies / Risk_factors_studies Limite: Animals / Humans / Male Idioma: En Revista: Nat Commun Assunto da revista: BIOLOGIA / CIENCIA Ano de publicação: 2017 Tipo de documento: Article País de afiliação: Estados Unidos
Texto completo
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XML
PubMed Links
Buscar no Google

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Doença de Huntington / Aldeído Liases / Células-Tronco Neurais Tipo de estudo: Etiology_studies / Incidence_studies / Observational_studies / Prognostic_studies / Risk_factors_studies Limite: Animals / Humans / Male Idioma: En Revista: Nat Commun Assunto da revista: BIOLOGIA / CIENCIA Ano de publicação: 2017 Tipo de documento: Article País de afiliação: Estados Unidos