Orofacial granulomatosis in a 12-year-old girl successfully treated with intravenous pulse corticosteroid therapy and chloroquine.
Pediatr Dermatol
; 34(6): e324-e327, 2017 Nov.
Article
em En
| MEDLINE
| ID: mdl-28940800
ABSTRACT
Orofacial granulomatosis, a rare disease in childhood, is characterized by orofacial swelling in the absence of systemic disease. We report the case of a 12-year-old girl with asymptomatic erythematous infiltration of her upper lip, cheeks, and chin that had persisted for more than 2 years; biopsy confirmed granuloma formation. Because a large area was affected, intralesional corticosteroids were inappropriate and six cycles of 3-day intravenous pulse corticosteroid therapy (dexamethasone 1.5mg/kg), repeated once after 4 weeks, was given. Our patient also received oral chloroquine and topical emollients. At the end of the sixth pulse cycle, the infiltration had completely resolved, leaving slight residual erythema.
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Base de dados:
MEDLINE
Assunto principal:
Cloroquina
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Antirreumáticos
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Granulomatose Orofacial
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Glucocorticoides
Limite:
Child
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Female
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Humans
Idioma:
En
Revista:
Pediatr Dermatol
Ano de publicação:
2017
Tipo de documento:
Article