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Intracellular response to process optimization and impact on productivity and product aggregates for a high-titer CHO cell process.
Handlogten, Michael W; Lee-O'Brien, Allison; Roy, Gargi; Levitskaya, Sophia V; Venkat, Raghavan; Singh, Shailendra; Ahuja, Sanjeev.
Afiliação
  • Handlogten MW; Cell Culture and Fermentation Sciences, MedImmune LLC, Gaithersburg, Maryland.
  • Lee-O'Brien A; Cell Culture and Fermentation Sciences, MedImmune LLC, Gaithersburg, Maryland.
  • Roy G; Antibody Discovery and Protein Engineering, MedImmune LLC, Gaithersburg, Maryland.
  • Levitskaya SV; Analytical Sciences, MedImmune LLC, Gaithersburg, Maryland.
  • Venkat R; Cell Culture and Fermentation Sciences, MedImmune LLC, Gaithersburg, Maryland.
  • Singh S; Biologics Development and Commercialization, West Point, Pennsylvania.
  • Ahuja S; Cell Culture and Fermentation Sciences, MedImmune LLC, Gaithersburg, Maryland.
Biotechnol Bioeng ; 115(1): 126-138, 2018 Jan.
Article em En | MEDLINE | ID: mdl-28941283

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Biotecnologia / Proteínas Recombinantes / Células CHO / Técnicas de Cultura de Células / Anticorpos Limite: Animals Idioma: En Revista: Biotechnol Bioeng Ano de publicação: 2018 Tipo de documento: Article

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Biotecnologia / Proteínas Recombinantes / Células CHO / Técnicas de Cultura de Células / Anticorpos Limite: Animals Idioma: En Revista: Biotechnol Bioeng Ano de publicação: 2018 Tipo de documento: Article