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In Vivo Imaging of Glutamine Metabolism to the Oncometabolite 2-Hydroxyglutarate in IDH1/2 Mutant Tumors.
Salamanca-Cardona, Lucia; Shah, Hardik; Poot, Alex J; Correa, Fabian M; Di Gialleonardo, Valentina; Lui, Hui; Miloushev, Vesselin Z; Granlund, Kristin L; Tee, Sui S; Cross, Justin R; Thompson, Craig B; Keshari, Kayvan R.
Afiliação
  • Salamanca-Cardona L; Department of Radiology, Memorial Sloan Kettering Cancer Center (MSKCC), New York, NY 10065, USA; Molecular Pharmacology Program, Memorial Sloan Kettering Cancer Center (MSKCC), New York, NY 10065, USA.
  • Shah H; Donald B. and Catherine C. Marron Cancer Metabolism Center, Memorial Sloan Kettering Cancer Center (MSKCC), New York, NY 10065, USA.
  • Poot AJ; Department of Radiology, Memorial Sloan Kettering Cancer Center (MSKCC), New York, NY 10065, USA; Molecular Pharmacology Program, Memorial Sloan Kettering Cancer Center (MSKCC), New York, NY 10065, USA.
  • Correa FM; Department of Radiology, Memorial Sloan Kettering Cancer Center (MSKCC), New York, NY 10065, USA; Molecular Pharmacology Program, Memorial Sloan Kettering Cancer Center (MSKCC), New York, NY 10065, USA.
  • Di Gialleonardo V; Department of Radiology, Memorial Sloan Kettering Cancer Center (MSKCC), New York, NY 10065, USA; Molecular Pharmacology Program, Memorial Sloan Kettering Cancer Center (MSKCC), New York, NY 10065, USA.
  • Lui H; Donald B. and Catherine C. Marron Cancer Metabolism Center, Memorial Sloan Kettering Cancer Center (MSKCC), New York, NY 10065, USA.
  • Miloushev VZ; Department of Radiology, Memorial Sloan Kettering Cancer Center (MSKCC), New York, NY 10065, USA; Molecular Pharmacology Program, Memorial Sloan Kettering Cancer Center (MSKCC), New York, NY 10065, USA.
  • Granlund KL; Department of Radiology, Memorial Sloan Kettering Cancer Center (MSKCC), New York, NY 10065, USA; Molecular Pharmacology Program, Memorial Sloan Kettering Cancer Center (MSKCC), New York, NY 10065, USA.
  • Tee SS; Department of Radiology, Memorial Sloan Kettering Cancer Center (MSKCC), New York, NY 10065, USA; Molecular Pharmacology Program, Memorial Sloan Kettering Cancer Center (MSKCC), New York, NY 10065, USA.
  • Cross JR; Donald B. and Catherine C. Marron Cancer Metabolism Center, Memorial Sloan Kettering Cancer Center (MSKCC), New York, NY 10065, USA.
  • Thompson CB; Cancer Biology and Genetics Program, Memorial Sloan Kettering Cancer Center (MSKCC), New York, NY 10065, USA.
  • Keshari KR; Department of Radiology, Memorial Sloan Kettering Cancer Center (MSKCC), New York, NY 10065, USA; Molecular Pharmacology Program, Memorial Sloan Kettering Cancer Center (MSKCC), New York, NY 10065, USA; Weill Cornell Medical College, New York, NY 10065, USA. Electronic address: rahimikk@mskcc.org.
Cell Metab ; 26(6): 830-841.e3, 2017 Dec 05.
Article em En | MEDLINE | ID: mdl-29056515

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Neoplasias Ósseas / Biomarcadores Tumorais / Condrossarcoma / Glutamina / Glutaratos / Isocitrato Desidrogenase Limite: Animals / Female / Humans / Male Idioma: En Revista: Cell Metab Assunto da revista: METABOLISMO Ano de publicação: 2017 Tipo de documento: Article País de afiliação: Estados Unidos

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Neoplasias Ósseas / Biomarcadores Tumorais / Condrossarcoma / Glutamina / Glutaratos / Isocitrato Desidrogenase Limite: Animals / Female / Humans / Male Idioma: En Revista: Cell Metab Assunto da revista: METABOLISMO Ano de publicação: 2017 Tipo de documento: Article País de afiliação: Estados Unidos