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The Structural Basis for Complement Inhibition by Gigastasin, a Protease Inhibitor from the Giant Amazon Leech.
Pang, Siew Siew; Wijeyewickrema, Lakshmi C; Hor, Lilian; Tan, Sheareen; Lameignere, Emilie; Conway, Edward M; Blom, Anna M; Mohlin, Frida C; Liu, Xuyu; Payne, Richard J; Whisstock, James C; Pike, Robert N.
Afiliação
  • Pang SS; Department of Biochemistry and Molecular Biology and Australian Research Council Centre of Excellence in Advanced Molecular Imaging, Biomedicine Discovery Institute, Monash University, Melbourne, Victoria 3800, Australia.
  • Wijeyewickrema LC; Department of Biochemistry and Genetics and Australian Research Council Centre of Excellence in Advanced Molecular Imaging, La Trobe Institute for Molecular Science, La Trobe University, Melbourne, Victoria 3086, Australia.
  • Hor L; Department of Biochemistry and Genetics and Australian Research Council Centre of Excellence in Advanced Molecular Imaging, La Trobe Institute for Molecular Science, La Trobe University, Melbourne, Victoria 3086, Australia.
  • Tan S; Department of Biochemistry and Molecular Biology and Australian Research Council Centre of Excellence in Advanced Molecular Imaging, Biomedicine Discovery Institute, Monash University, Melbourne, Victoria 3800, Australia.
  • Lameignere E; Centre for Blood Research, Department of Medicine, Faculty of Medicine, University of British Columbia, Vancouver, British Columbia V6T 1Z3, Canada.
  • Conway EM; Centre for Blood Research, Department of Medicine, Faculty of Medicine, University of British Columbia, Vancouver, British Columbia V6T 1Z3, Canada.
  • Blom AM; Division of Medical Protein Chemistry, Department of Translational Medicine, Lund University, Malmö SE-221 00, Sweden; and.
  • Mohlin FC; Division of Medical Protein Chemistry, Department of Translational Medicine, Lund University, Malmö SE-221 00, Sweden; and.
  • Liu X; School of Chemistry, The University of Sydney, Sydney, New South Wales 2006, Australia.
  • Payne RJ; School of Chemistry, The University of Sydney, Sydney, New South Wales 2006, Australia.
  • Whisstock JC; Department of Biochemistry and Molecular Biology and Australian Research Council Centre of Excellence in Advanced Molecular Imaging, Biomedicine Discovery Institute, Monash University, Melbourne, Victoria 3800, Australia; r.pike@latrobe.edu.au james.whisstock@monash.edu.
  • Pike RN; Department of Biochemistry and Genetics and Australian Research Council Centre of Excellence in Advanced Molecular Imaging, La Trobe Institute for Molecular Science, La Trobe University, Melbourne, Victoria 3086, Australia; r.pike@latrobe.edu.au james.whisstock@monash.edu.
J Immunol ; 199(11): 3883-3891, 2017 12 01.
Article em En | MEDLINE | ID: mdl-29061764
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Peptídeos / Complemento C1 / Inibidores de Serina Proteinase / Ativação do Complemento / Via Clássica do Complemento / Lectina de Ligação a Manose da Via do Complemento / Serina Proteases Associadas a Proteína de Ligação a Manose / Inativadores do Complemento / Sanguessugas Limite: Animals / Humans Idioma: En Revista: J Immunol Ano de publicação: 2017 Tipo de documento: Article País de afiliação: Austrália
Texto completo
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PubMed Links
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Peptídeos / Complemento C1 / Inibidores de Serina Proteinase / Ativação do Complemento / Via Clássica do Complemento / Lectina de Ligação a Manose da Via do Complemento / Serina Proteases Associadas a Proteína de Ligação a Manose / Inativadores do Complemento / Sanguessugas Limite: Animals / Humans Idioma: En Revista: J Immunol Ano de publicação: 2017 Tipo de documento: Article País de afiliação: Austrália