Ocular Signs Related to Overweight and Arterial Hypertension in Children: A Systematic Review.
Open Ophthalmol J
; 11: 273-285, 2017.
Article
em En
| MEDLINE
| ID: mdl-29081867
ABSTRACT
BACKGROUND:
The ocular effects of obesity and hypertension need to be established and can be used as prognostic markers.OBJECTIVE:
To estimate the prevalence of ophthalmological alterations in children and adolescents who are overweight and/or have SAH.METHODS:
The database for this study included all observational studies (CS, cohort, case-control and "baseline" description of randomized clinical trials) with children and/or adolescents who were overweight, obese or had SAH and that measured ophthalmological alterations.RESULTS:
Comparative studies with healthy children demonstrated positive association between body adiposity with retinal venular dilation, and SAH with retinal arteriolar narrowing. Different retinal fundus cameras and computer-assisted programs to evaluate the retinal vessels, variations in the methods of analysis, adjustments, populations, were the main arguments against formal meta-analysis. The heterogeneity was too high (I2 >90%, in fixed or randomized effects), and the lack of linearity, normal distribution and homoscedasticity did not recommend meta-regression.CONCLUSION:
Obesity and SAH show associations with ophthalmological alterations, especially with retinal vessel diameter. Lack of standardization does not allow a quantitative evaluation.
Texto completo:
1
Base de dados:
MEDLINE
Tipo de estudo:
Clinical_trials
/
Diagnostic_studies
/
Observational_studies
/
Risk_factors_studies
/
Systematic_reviews
Idioma:
En
Revista:
Open Ophthalmol J
Ano de publicação:
2017
Tipo de documento:
Article
País de afiliação:
Brasil