Cytogenetic analysis of ten human seminomas.

Castedo, S M; de Jong, B; Oosterhuis, J W; Seruca, R; te Meerman, G J; Dam, A; Schraffordt Koops, H

Castedo, S M; de Jong, B; Oosterhuis, J W; Seruca, R; te Meerman, G J; Dam, A; Schraffordt Koops, H.

Afiliação

Castedo SM; Department of Human Genetics, State University of Groningen, The Netherlands.

Cancer Res ; 49(2): 439-43, 1989 Jan 15.

Article em En | MEDLINE | ID: mdl-2910461

ABSTRACT

ABSTRACT

A cytogenetic analysis of ten seminomas has been carried out after direct harvesting of the tumor cells. Modal chromosome numbers ranged from 63 to 112. These numbers were in agreement with flow cytometric determination of the DNA content of the tumors. Eight tumors had at least one copy of an i(12p) among other chromosomal abnormalities. Two seminomas lacked the i(12p).

Assuntos

Disgerminoma/genética; Neoplasias Testiculares/genética; Adulto; Aberrações Cromossômicas; Transtornos Cromossômicos; DNA de Neoplasias/análise; Humanos; Cariotipagem; Masculino; Pessoa de Meia-Idade

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Base de dados: MEDLINE Assunto principal: Neoplasias Testiculares / Disgerminoma Limite: Adult / Humans / Male / Middle aged Idioma: En Revista: Cancer Res Ano de publicação: 1989 Tipo de documento: Article País de afiliação: Holanda

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