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Tumor-targeting efficacy of a BF211 prodrug through hydrolysis by fibroblast activation protein-α.
Chai, Xiao-Ping; Sun, Guang-Long; Fang, Yan-Fen; Hu, Li-Hong; Liu, Xuan; Zhang, Xiong-Wen.
Afiliação
  • Chai XP; Shanghai Engineering Research Center of Molecular Therapeutics and New Drug Development, School of Chemistry and Molecular Engineering, East China Normal University, Shanghai 200241, China.
  • Sun GL; Jiangsu Key Laboratory for Functional Substance of Chinese Medicine, Jiangsu Collaborative Innovation Center of Chinese Medicinal Resources Industrialization, Stake Key Laboratory Cultivation Base for TCM Quality and Efficacy, School of Pharmacy, Nanjing University of Chinese Medicine, Nanjing 21002
  • Fang YF; Shanghai Engineering Research Center of Molecular Therapeutics and New Drug Development, School of Chemistry and Molecular Engineering, East China Normal University, Shanghai 200241, China.
  • Hu LH; Jiangsu Key Laboratory for Functional Substance of Chinese Medicine, Jiangsu Collaborative Innovation Center of Chinese Medicinal Resources Industrialization, Stake Key Laboratory Cultivation Base for TCM Quality and Efficacy, School of Pharmacy, Nanjing University of Chinese Medicine, Nanjing 21002
  • Liu X; Renji Hospital, School of Medicine, Shanghai Jiaotong University, Shanghai 200127, China.
  • Zhang XW; Shanghai Engineering Research Center of Molecular Therapeutics and New Drug Development, School of Chemistry and Molecular Engineering, East China Normal University, Shanghai 200241, China.
Acta Pharmacol Sin ; 39(3): 415-424, 2018 Mar.
Article em En | MEDLINE | ID: mdl-29119969
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Piperazinas / Bufanolídeos / Pró-Fármacos / Serina Endopeptidases / Gelatinases / Dipeptídeos / Proteínas de Membrana Limite: Animals / Humans Idioma: En Revista: Acta Pharmacol Sin Assunto da revista: FARMACOLOGIA Ano de publicação: 2018 Tipo de documento: Article País de afiliação: China
Texto completo
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XML
PubMed Links
Buscar no Google

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Piperazinas / Bufanolídeos / Pró-Fármacos / Serina Endopeptidases / Gelatinases / Dipeptídeos / Proteínas de Membrana Limite: Animals / Humans Idioma: En Revista: Acta Pharmacol Sin Assunto da revista: FARMACOLOGIA Ano de publicação: 2018 Tipo de documento: Article País de afiliação: China