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Utility of a Power Aspiration-Based Extraction Technique as an Initial and Secondary Approach in the Treatment of Peripheral Arterial Thromboembolism: Results of the Multicenter PRISM Trial.
Saxon, Richard R; Benenati, James F; Teigen, Corey; Adams, George L; Sewall, Luke E.
Afiliação
  • Saxon RR; San Diego Cardiac and Vascular Institute, San Diego Imaging Medical Group, PO Box 23540, San Diego, CA 92193-3540. Electronic address: rsaxon5@gmail.com.
  • Benenati JF; Miami Cardiac and Vascular Institute, Baptist Hospital, Miami, Florida.
  • Teigen C; Interventional Radiology, Sanford Health, Fargo, North Dakota.
  • Adams GL; Interventional Cardiology, University of North Carolina Rex Healthcare, Raleigh, North Carolina.
  • Sewall LE; VIR Chicago, Hinsdale, Illinois.
J Vasc Interv Radiol ; 29(1): 92-100, 2018 Jan.
Article em En | MEDLINE | ID: mdl-29128156
ABSTRACT

PURPOSE:

To investigate the safety and initial efficacy of XTRACT, a power aspiration-based extraction technique for treatment of peripheral arterial thromboembolism with the use of the Penumbra/Indigo system. MATERIALS AND

METHODS:

A total of 79 patients were enrolled 39 (49.4%) underwent XTRACT as the initial therapy and 40 (50.6%) underwent XTRACT after failed catheter-directed thrombolysis or other mechanical intervention or for removal of distal emboli that occurred during an intervention. Occlusion locations were as follows 36.7% (n = 29) in the profunda, common, or superficial femoral artery; 35.4% (n = 28) in the popliteal artery; 15.2% (n = 12) in the tibial artery; 7.6% (n = 6) in the peroneal artery; and the remainder in the common iliac (n = 1), external iliac (n = 1), sciatic (n = 1), and brachial (n = 1) arteries.

RESULTS:

Complete or near-complete revascularization (Thrombolysis In Myocardial Infarction [TIMI] grade 2/3 flow) was achieved in 87.2% of patients (68 of 78) immediately after the XTRACT procedure and before any other intervention. Successful revascularization was achieved in 79.5% of patients (31 of 39) as an initial treatment and in 92.5% (37 of 40) as salvage or secondary therapy. After additional adjunctive endovascular interventions, TIMI grade 2/3 flow was achieved in 96.2% of patients (76 of 79). Complete thrombus removal and restoration of normal flow (TIMI grade 3) was achieved in 77.2% of patients (61 of 79) after all endovascular treatment was completed. No patients required surgical revascularization. No device-related adverse events occurred.

CONCLUSIONS:

XTRACT was safe and effective for revascularization of acute or subacute peripheral arterial occlusions as a primary therapy or as a secondary therapy after other endovascular techniques had failed.
Assuntos

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Tromboembolia / Trombectomia / Doença Arterial Periférica / Procedimentos Endovasculares / Perna (Membro) Tipo de estudo: Observational_studies Limite: Adult / Aged / Aged80 / Female / Humans / Male / Middle aged País/Região como assunto: America do norte Idioma: En Revista: J Vasc Interv Radiol Assunto da revista: ANGIOLOGIA / RADIOLOGIA Ano de publicação: 2018 Tipo de documento: Article

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Tromboembolia / Trombectomia / Doença Arterial Periférica / Procedimentos Endovasculares / Perna (Membro) Tipo de estudo: Observational_studies Limite: Adult / Aged / Aged80 / Female / Humans / Male / Middle aged País/Região como assunto: America do norte Idioma: En Revista: J Vasc Interv Radiol Assunto da revista: ANGIOLOGIA / RADIOLOGIA Ano de publicação: 2018 Tipo de documento: Article