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Selective and membrane-permeable small molecule inhibitors of nicotinamide N-methyltransferase reverse high fat diet-induced obesity in mice.
Neelakantan, Harshini; Vance, Virginia; Wetzel, Michael D; Wang, Hua-Yu Leo; McHardy, Stanton F; Finnerty, Celeste C; Hommel, Jonathan D; Watowich, Stanley J.
Afiliação
  • Neelakantan H; Department of Biochemistry and Molecular Biology, University of Texas Medical Branch, Galveston, TX 77550, USA.
  • Vance V; Department of Biochemistry and Molecular Biology, University of Texas Medical Branch, Galveston, TX 77550, USA.
  • Wetzel MD; Department of Surgery, University of Texas Medical Branch, Galveston, TX 77550 USA; Shriners Hospitals for Children-Galveston, Galveston, TX 77550, USA.
  • Wang HL; Department of Chemistry and Center for Innovative Drug Discovery, University of Texas at San Antonio, San Antonio, TX 78249, USA.
  • McHardy SF; Department of Chemistry and Center for Innovative Drug Discovery, University of Texas at San Antonio, San Antonio, TX 78249, USA.
  • Finnerty CC; Department of Surgery, University of Texas Medical Branch, Galveston, TX 77550 USA; Shriners Hospitals for Children-Galveston, Galveston, TX 77550, USA.
  • Hommel JD; Department of Pharmacology and Toxicology, University of Texas Medical Branch, Galveston, TX 77550, USA.
  • Watowich SJ; Department of Biochemistry and Molecular Biology, University of Texas Medical Branch, Galveston, TX 77550, USA. Electronic address: watowich@xray.utmb.edu.
Biochem Pharmacol ; 147: 141-152, 2018 01.
Article em En | MEDLINE | ID: mdl-29155147
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Permeabilidade da Membrana Celular / Nicotinamida N-Metiltransferase / Dieta Hiperlipídica / Obesidade Limite: Animals / Humans / Male Idioma: En Revista: Biochem Pharmacol Ano de publicação: 2018 Tipo de documento: Article País de afiliação: Estados Unidos
Texto completo
Imprimir
XML
PubMed Links
Buscar no Google

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Permeabilidade da Membrana Celular / Nicotinamida N-Metiltransferase / Dieta Hiperlipídica / Obesidade Limite: Animals / Humans / Male Idioma: En Revista: Biochem Pharmacol Ano de publicação: 2018 Tipo de documento: Article País de afiliação: Estados Unidos