Moderate to severe psoriasis treatment challenges through the era of biological drugs.
An Bras Dermatol
; 92(5): 668-674, 2017.
Article
em En
| MEDLINE
| ID: mdl-29166504
ABSTRACT
Biological therapy has revolutionized moderate to severe psoriasis treatment. However, despite being more effective than conventional systemic treatments, some patients do not respond or lose response to biotechnological treatments or develop drug-antibodies, interfering with its safety and efficacy. There are also clinical forms of the disease and patient profiles for which is pending further scientific evidence for more sustained therapeutic interventions. The continuous and more detailed knowledge of psoriasis pathophysiology has allowed identifying new therapeutic targets, which is expected to help overcome the challenges of individualized psoriasis treatment.
Texto completo:
1
Base de dados:
MEDLINE
Assunto principal:
Psoríase
Tipo de estudo:
Prognostic_studies
Limite:
Humans
Idioma:
En
Revista:
An Bras Dermatol
Ano de publicação:
2017
Tipo de documento:
Article
País de afiliação:
Portugal