Paracoccidioidomycosis: Current Perspectives from Brazil.
Open Microbiol J
; 11: 224-282, 2017.
Article
em En
| MEDLINE
| ID: mdl-29204222
ABSTRACT
BACKGROUND:
This review article summarizes and updates the knowledge on paracoccidioidomycosis. P lutzii and the cryptic species of P. brasiliensis and their geographical distribution in Latin America, explaining the difficulties observed in the serological diagnosis.OBJECTIVES:
Emphasis has been placed on some genetic factors as predisposing condition for paracoccidioidomycosis. Veterinary aspects were focused, showing the wide distribution of infection among animals. The cell-mediated immunity was better characterized, incorporating the recent findings.METHODS:
Serological methods for diagnosis were also compared for their parameters of accuracy, including the analysis of relapse.RESULTS:
Clinical forms have been better classified in order to include the pictures less frequently observesiod.CONCLUSION:
Itraconazole and the trimethoprim-sulfamethoxazole combination was compared regarding efficacy, effectiveness and safety, demonstrating that azole should be the first choice in the treatment of paracoccidioidomycosis.
Texto completo:
1
Base de dados:
MEDLINE
País/Região como assunto:
America do sul
/
Brasil
Idioma:
En
Revista:
Open Microbiol J
Ano de publicação:
2017
Tipo de documento:
Article
País de afiliação:
Brasil