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Structure-function analysis of ferroportin defines the binding site and an alternative mechanism of action of hepcidin.
Aschemeyer, Sharraya; Qiao, Bo; Stefanova, Deborah; Valore, Erika V; Sek, Albert C; Ruwe, T Alex; Vieth, Kyle R; Jung, Grace; Casu, Carla; Rivella, Stefano; Jormakka, Mika; Mackenzie, Bryan; Ganz, Tomas; Nemeth, Elizabeta.
Afiliação
  • Aschemeyer S; Molecular Biology Interdepartmental Doctoral Program.
  • Qiao B; Department of Medicine, and.
  • Stefanova D; Department of Medicine, and.
  • Valore EV; Department of Molecular, Cellular, and Integrative Physiology, David Geffen School of Medicine, University of California, Los Angeles, Los Angeles, CA.
  • Sek AC; Department of Medicine, and.
  • Ruwe TA; Department of Molecular, Cellular, and Integrative Physiology, David Geffen School of Medicine, University of California, Los Angeles, Los Angeles, CA.
  • Vieth KR; Department of Molecular and Cellular Physiology, University of Cincinnati College of Medicine, Cincinnati, OH.
  • Jung G; Department of Molecular and Cellular Physiology, University of Cincinnati College of Medicine, Cincinnati, OH.
  • Casu C; Department of Medicine, and.
  • Rivella S; Division of Hematology, Department of Pediatrics, Children's Hospital of Philadelphia, Philadelphia, PA.
  • Jormakka M; Division of Hematology, Department of Pediatrics, Children's Hospital of Philadelphia, Philadelphia, PA.
  • Mackenzie B; Structural Biology Program, Centenary Institute, and.
  • Ganz T; Faculty of Medicine, University of Sydney, Sydney, Australia; and.
  • Nemeth E; Department of Molecular and Cellular Physiology, University of Cincinnati College of Medicine, Cincinnati, OH.
Blood ; 131(8): 899-910, 2018 02 22.
Article em En | MEDLINE | ID: mdl-29237594

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Resistência a Medicamentos / Proteínas de Transporte de Cátions / Hepcidinas / Ferro Limite: Animals / Humans Idioma: En Revista: Blood Ano de publicação: 2018 Tipo de documento: Article

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Resistência a Medicamentos / Proteínas de Transporte de Cátions / Hepcidinas / Ferro Limite: Animals / Humans Idioma: En Revista: Blood Ano de publicação: 2018 Tipo de documento: Article