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Inhibiting DPP4 in a mouse model of HHT1 results in a shift towards regenerative macrophages and reduces fibrosis after myocardial infarction.
Dingenouts, Calinda K E; Bakker, Wineke; Lodder, Kirsten; Wiesmeijer, Karien C; Moerkamp, Asja T; Maring, Janita A; Arthur, Helen M; Smits, Anke M; Goumans, Marie-José.
Afiliação
  • Dingenouts CKE; Department of Molecular Cell Biology, Leiden University Medical Center, Leiden, the Netherlands.
  • Bakker W; Department of Molecular Cell Biology, Leiden University Medical Center, Leiden, the Netherlands.
  • Lodder K; Department of Molecular Cell Biology, Leiden University Medical Center, Leiden, the Netherlands.
  • Wiesmeijer KC; Department of Molecular Cell Biology, Leiden University Medical Center, Leiden, the Netherlands.
  • Moerkamp AT; Department of Molecular Cell Biology, Leiden University Medical Center, Leiden, the Netherlands.
  • Maring JA; Department of Molecular Cell Biology, Leiden University Medical Center, Leiden, the Netherlands.
  • Arthur HM; Institute of Genetic Medicine, Newcastle University, International Centre for Life, Newcastle upon Tyne, United Kingdom.
  • Smits AM; Department of Molecular Cell Biology, Leiden University Medical Center, Leiden, the Netherlands.
  • Goumans MJ; Department of Molecular Cell Biology, Leiden University Medical Center, Leiden, the Netherlands.
PLoS One ; 12(12): e0189805, 2017.
Article em En | MEDLINE | ID: mdl-29253907
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Telangiectasia Hemorrágica Hereditária / Dipeptidil Peptidase 4 / Inibidores da Dipeptidil Peptidase IV / Macrófagos / Infarto do Miocárdio Tipo de estudo: Prognostic_studies Limite: Animals / Humans / Male Idioma: En Revista: PLoS One Assunto da revista: CIENCIA / MEDICINA Ano de publicação: 2017 Tipo de documento: Article País de afiliação: Holanda
Texto completo
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XML
PubMed Links
Buscar no Google

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Telangiectasia Hemorrágica Hereditária / Dipeptidil Peptidase 4 / Inibidores da Dipeptidil Peptidase IV / Macrófagos / Infarto do Miocárdio Tipo de estudo: Prognostic_studies Limite: Animals / Humans / Male Idioma: En Revista: PLoS One Assunto da revista: CIENCIA / MEDICINA Ano de publicação: 2017 Tipo de documento: Article País de afiliação: Holanda