Brd4 binds to active enhancers to control cell identity gene induction in adipogenesis and myogenesis.

Lee, Ji-Eun; Park, Young-Kwon; Park, Sarah; Jang, Younghoon; Waring, Nicholas; Dey, Anup; Ozato, Keiko; Lai, Binbin; Peng, Weiqun; Ge, Kai

Lee, Ji-Eun; Park, Young-Kwon; Park, Sarah; Jang, Younghoon; Waring, Nicholas; Dey, Anup; Ozato, Keiko; Lai, Binbin; Peng, Weiqun; Ge, Kai.

Afiliação

Lee JE; Adipocyte Biology and Gene Regulation Section, Laboratory of Endocrinology and Receptor Biology, National Institute of Diabetes and Digestive and Kidney Diseases, National Institutes of Health, Bethesda, MD, 20892, USA.
Park YK; Adipocyte Biology and Gene Regulation Section, Laboratory of Endocrinology and Receptor Biology, National Institute of Diabetes and Digestive and Kidney Diseases, National Institutes of Health, Bethesda, MD, 20892, USA.
Park S; Adipocyte Biology and Gene Regulation Section, Laboratory of Endocrinology and Receptor Biology, National Institute of Diabetes and Digestive and Kidney Diseases, National Institutes of Health, Bethesda, MD, 20892, USA.
Jang Y; Adipocyte Biology and Gene Regulation Section, Laboratory of Endocrinology and Receptor Biology, National Institute of Diabetes and Digestive and Kidney Diseases, National Institutes of Health, Bethesda, MD, 20892, USA.
Waring N; Adipocyte Biology and Gene Regulation Section, Laboratory of Endocrinology and Receptor Biology, National Institute of Diabetes and Digestive and Kidney Diseases, National Institutes of Health, Bethesda, MD, 20892, USA.
Dey A; Departments of Physics and Anatomy and Regenerative Biology, The George Washington University, Washington, DC, 20052, USA.
Ozato K; Program in Genomics of Differentiation, National Institute of Child Health and Human Development, National Institutes of Health, Bethesda, MD, 20892, USA.
Lai B; Program in Genomics of Differentiation, National Institute of Child Health and Human Development, National Institutes of Health, Bethesda, MD, 20892, USA.
Peng W; Adipocyte Biology and Gene Regulation Section, Laboratory of Endocrinology and Receptor Biology, National Institute of Diabetes and Digestive and Kidney Diseases, National Institutes of Health, Bethesda, MD, 20892, USA.
Ge K; Departments of Physics and Anatomy and Regenerative Biology, The George Washington University, Washington, DC, 20052, USA.

Nat Commun ; 8(1): 2217, 2017 12 20.

Article em En | MEDLINE | ID: mdl-29263365

Assuntos

Adipogenia/genética; Desenvolvimento Muscular/genética; Proteínas Nucleares/genética; Fatores de Transcrição/genética; Animais; Diferenciação Celular/genética; Linhagem da Célula; Elementos Facilitadores Genéticos; Epigênese Genética; Regulação da Expressão Gênica; Código das Histonas; Histona-Lisina N-Metiltransferase/metabolismo; Camundongos; Camundongos Knockout; Proteínas Nucleares/metabolismo; RNA Polimerase II/metabolismo; Fatores de Transcrição/metabolismo; Fatores de Transcrição de p300-CBP/metabolismo

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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Fatores de Transcrição / Proteínas Nucleares / Desenvolvimento Muscular / Adipogenia Tipo de estudo: Prognostic_studies Limite: Animals Idioma: En Revista: Nat Commun Assunto da revista: BIOLOGIA / CIENCIA Ano de publicação: 2017 Tipo de documento: Article País de afiliação: Estados Unidos

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