Reliability of the Apathy Evaluation Scale in Myotonic Dystrophy Type 1.
J Neuromuscul Dis
; 5(1): 39-46, 2018.
Article
em En
| MEDLINE
| ID: mdl-29278897
ABSTRACT
BACKGROUND:
Apathy is a common debilitating symptom of myotonic dystrophy type 1 (DM1). The Apathy Evaluation Scale (AES) has been identified as a promising measurement instrument to be used in DM1 but its metrological properties must be further documented.OBJECTIVE:
To determine the internal consistency of the Self (AES-S), Informant (AES-I), and Clinician (AES-C) versions of the AES and to assess the test-retest reliability, standard error of measurement, and minimal detectable change of the AES-S and AES-I in a sample of DM1 patients and their related informants.RESULTS:
All scales showed good internal consistency (Cronbach's alpha 0.83-0.87) and the AES-S and AES-I showed good test-retest reliability (ICCâ=â0.79-0.91). Additionally, clinicians and informants had a tendency to overestimate DM1 patients' level of apathy compared to patients' self-ratings, suggesting potentially impaired self-awareness in DM1 patients.CONCLUSIONS:
The present results advocate the use of the AES-I as a reliable instrument to estimate apathy in DM1 patients for either clinical or research purposes, and support the relevance to pursue the assessment of metrological properties of the AES as a tool of great value for the development of outcomes for clinical trial readiness in DM1.Palavras-chave
Texto completo:
1
Base de dados:
MEDLINE
Assunto principal:
Pessoal de Saúde
/
Autorrelato
/
Apatia
/
Distrofia Miotônica
Tipo de estudo:
Clinical_trials
/
Prognostic_studies
/
Qualitative_research
Limite:
Adult
/
Female
/
Humans
/
Male
/
Middle aged
Idioma:
En
Revista:
J Neuromuscul Dis
Ano de publicação:
2018
Tipo de documento:
Article
País de afiliação:
Canadá