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Discovery of selective, orally bioavailable inhibitor of mouse chitotriosidase.
Mazur, Marzena; Bartoszewicz, Agnieszka; Dymek, Barbara; Salamon, Magdalena; Andryianau, Gleb; Kowalski, Michal; Olejniczak, Sylwia; Matyszewski, Krzysztof; Pluta, Elzbieta; Borek, Bartlomiej; Stefaniak, Filip; Zagozdzon, Agnieszka; Mazurkiewicz, Marcin; Koralewski, Robert; Czestkowski, Wojciech; Piotrowicz, Michal; Niedziejko, Piotr; Gruza, Mariusz M; Dzwonek, Karolina; Golebiowski, Adam; Golab, Jakub; Olczak, Jacek.
Afiliação
  • Mazur M; OncoArendi Therapeutics SA, Zwirki i Wigury 101, 02-089 Warsaw, Poland.
  • Bartoszewicz A; OncoArendi Therapeutics SA, Zwirki i Wigury 101, 02-089 Warsaw, Poland. Electronic address: a.bartoszewicz@oncoarendi.com.
  • Dymek B; OncoArendi Therapeutics SA, Zwirki i Wigury 101, 02-089 Warsaw, Poland.
  • Salamon M; OncoArendi Therapeutics SA, Zwirki i Wigury 101, 02-089 Warsaw, Poland.
  • Andryianau G; OncoArendi Therapeutics SA, Zwirki i Wigury 101, 02-089 Warsaw, Poland.
  • Kowalski M; OncoArendi Therapeutics SA, Zwirki i Wigury 101, 02-089 Warsaw, Poland.
  • Olejniczak S; OncoArendi Therapeutics SA, Zwirki i Wigury 101, 02-089 Warsaw, Poland.
  • Matyszewski K; OncoArendi Therapeutics SA, Zwirki i Wigury 101, 02-089 Warsaw, Poland.
  • Pluta E; OncoArendi Therapeutics SA, Zwirki i Wigury 101, 02-089 Warsaw, Poland.
  • Borek B; OncoArendi Therapeutics SA, Zwirki i Wigury 101, 02-089 Warsaw, Poland.
  • Stefaniak F; OncoArendi Therapeutics SA, Zwirki i Wigury 101, 02-089 Warsaw, Poland; Laboratory of Bioinformatics and Protein Engineering, International Institute of Molecular and Cell Biology in Warsaw, Ks. Trojdena 4, 02-109 Warsaw, Poland.
  • Zagozdzon A; OncoArendi Therapeutics SA, Zwirki i Wigury 101, 02-089 Warsaw, Poland.
  • Mazurkiewicz M; OncoArendi Therapeutics SA, Zwirki i Wigury 101, 02-089 Warsaw, Poland.
  • Koralewski R; OncoArendi Therapeutics SA, Zwirki i Wigury 101, 02-089 Warsaw, Poland.
  • Czestkowski W; OncoArendi Therapeutics SA, Zwirki i Wigury 101, 02-089 Warsaw, Poland.
  • Piotrowicz M; OncoArendi Therapeutics SA, Zwirki i Wigury 101, 02-089 Warsaw, Poland.
  • Niedziejko P; OncoArendi Therapeutics SA, Zwirki i Wigury 101, 02-089 Warsaw, Poland.
  • Gruza MM; OncoArendi Therapeutics SA, Zwirki i Wigury 101, 02-089 Warsaw, Poland.
  • Dzwonek K; OncoArendi Therapeutics SA, Zwirki i Wigury 101, 02-089 Warsaw, Poland.
  • Golebiowski A; OncoArendi Therapeutics SA, Zwirki i Wigury 101, 02-089 Warsaw, Poland.
  • Golab J; OncoArendi Therapeutics SA, Zwirki i Wigury 101, 02-089 Warsaw, Poland; Department of Immunology, Medical University of Warsaw, Banacha 1a, 02-097 Warsaw, Poland.
  • Olczak J; OncoArendi Therapeutics SA, Zwirki i Wigury 101, 02-089 Warsaw, Poland.
Bioorg Med Chem Lett ; 28(3): 310-314, 2018 02 01.
Article em En | MEDLINE | ID: mdl-29292229
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Bibliotecas de Moléculas Pequenas / Descoberta de Drogas / Hexosaminidases Limite: Animals Idioma: En Revista: Bioorg Med Chem Lett Assunto da revista: BIOQUIMICA / QUIMICA Ano de publicação: 2018 Tipo de documento: Article País de afiliação: Polônia
Texto completo
Imprimir
XML
PubMed Links
Buscar no Google

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Bibliotecas de Moléculas Pequenas / Descoberta de Drogas / Hexosaminidases Limite: Animals Idioma: En Revista: Bioorg Med Chem Lett Assunto da revista: BIOQUIMICA / QUIMICA Ano de publicação: 2018 Tipo de documento: Article País de afiliação: Polônia