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Synthesis of Multisubstituted Azatriphenylenes by Iridium-Catalyzed [2 + 2 + 2] Cycloaddition of Biaryl-Linked Diynes with Nitriles.
Takeuchi, Ryo; Fujisawa, Shunsuke; Yoshida, Yuzo; Sagano, Jun; Hashimoto, Toru; Matsunami, Asuka.
Afiliação
  • Takeuchi R; Department of Chemistry and Biological Science, Aoyama Gakuin University , 5-10-1 Fuchinobe, Chuo, Sagamihara, Kanagawa 252-5258, Japan.
  • Fujisawa S; Department of Chemistry and Biological Science, Aoyama Gakuin University , 5-10-1 Fuchinobe, Chuo, Sagamihara, Kanagawa 252-5258, Japan.
  • Yoshida Y; Department of Chemistry and Biological Science, Aoyama Gakuin University , 5-10-1 Fuchinobe, Chuo, Sagamihara, Kanagawa 252-5258, Japan.
  • Sagano J; Department of Chemistry and Biological Science, Aoyama Gakuin University , 5-10-1 Fuchinobe, Chuo, Sagamihara, Kanagawa 252-5258, Japan.
  • Hashimoto T; Department of Chemistry and Biological Science, Aoyama Gakuin University , 5-10-1 Fuchinobe, Chuo, Sagamihara, Kanagawa 252-5258, Japan.
  • Matsunami A; Department of Chemistry and Biological Science, Aoyama Gakuin University , 5-10-1 Fuchinobe, Chuo, Sagamihara, Kanagawa 252-5258, Japan.
J Org Chem ; 83(4): 1852-1860, 2018 02 16.
Article em En | MEDLINE | ID: mdl-29308650
A convenient synthesis of multisubstituted azatriphenylenes is reported. [Ir(cod)Cl]2/diphosphine is an efficient catalyst for the [2 + 2 + 2] cycloaddition of biaryl-linked diynes with nitriles to give multisubstituted azatriphenylenes in high yields. Aromatic, heteroaromatic, aliphatic, and functionalized nitriles could be used for the reaction.

Texto completo: 1 Base de dados: MEDLINE Idioma: En Revista: J Org Chem Ano de publicação: 2018 Tipo de documento: Article País de afiliação: Japão

Texto completo: 1 Base de dados: MEDLINE Idioma: En Revista: J Org Chem Ano de publicação: 2018 Tipo de documento: Article País de afiliação: Japão