RNA-Seq Highlights High Clonal Variation in Monoclonal Antibody Producing CHO Cells.

Orellana, Camila A; Marcellin, Esteban; Palfreyman, Robin W; Munro, Trent P; Gray, Peter P; Nielsen, Lars K

Orellana, Camila A; Marcellin, Esteban; Palfreyman, Robin W; Munro, Trent P; Gray, Peter P; Nielsen, Lars K.

Afiliação

Orellana CA; Australian Institute for Bioengineering and Nanotechnology (AIBN), The University of Queensland, Brisbane QLD 4072, Australia.
Marcellin E; Australian Institute for Bioengineering and Nanotechnology (AIBN), The University of Queensland, Brisbane QLD 4072, Australia.
Palfreyman RW; Metabolomics Australia (Queensland Node), The University of Queensland, Brisbane QLD 4072, Australia.
Munro TP; Australian Institute for Bioengineering and Nanotechnology (AIBN), The University of Queensland, Brisbane QLD 4072, Australia.
Gray PP; Australian Institute for Bioengineering and Nanotechnology (AIBN), The University of Queensland, Brisbane QLD 4072, Australia.
Nielsen LK; Australian Institute for Bioengineering and Nanotechnology (AIBN), The University of Queensland, Brisbane QLD 4072, Australia.

Biotechnol J ; 13(3): e1700231, 2018 Mar.

Article em En | MEDLINE | ID: mdl-29316330

Assuntos

Anticorpos Monoclonais/biossíntese; Células CHO; Evolução Clonal/genética; Sequenciamento de Nucleotídeos em Larga Escala; Animais; Linhagem da Célula/genética; Cricetulus

Palavras-chave

Chinese hamster ovary cells; RNA sequencing; clonal variation; monoclonal antibody; protein intracellular transport

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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Células CHO / Sequenciamento de Nucleotídeos em Larga Escala / Evolução Clonal / Anticorpos Monoclonais Limite: Animals Idioma: En Revista: Biotechnol J Assunto da revista: BIOTECNOLOGIA Ano de publicação: 2018 Tipo de documento: Article País de afiliação: Austrália

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