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A mass spectrometry imaging approach for investigating how drug-drug interactions influence drug blood-brain barrier permeability.
Vallianatou, Theodosia; Strittmatter, Nicole; Nilsson, Anna; Shariatgorji, Mohammadreza; Hamm, Gregory; Pereira, Marcela; Källback, Patrik; Svenningsson, Per; Karlgren, Maria; Goodwin, Richard J A; Andrén, Per E.
Afiliação
  • Vallianatou T; Biomolecular Mass Spectrometry Imaging, National Resource for Mass Spectrometry Imaging, Science for Life Laboratory, Department of Pharmaceutical Biosciences, Uppsala University, Box 591, SE-75124, Uppsala, Sweden.
  • Strittmatter N; Pathology Sciences, Drug Safety and Metabolism, IMED Biotech Unit, AstraZeneca, Cambridge, UK.
  • Nilsson A; Biomolecular Mass Spectrometry Imaging, National Resource for Mass Spectrometry Imaging, Science for Life Laboratory, Department of Pharmaceutical Biosciences, Uppsala University, Box 591, SE-75124, Uppsala, Sweden.
  • Shariatgorji M; Biomolecular Mass Spectrometry Imaging, National Resource for Mass Spectrometry Imaging, Science for Life Laboratory, Department of Pharmaceutical Biosciences, Uppsala University, Box 591, SE-75124, Uppsala, Sweden.
  • Hamm G; Pathology Sciences, Drug Safety and Metabolism, IMED Biotech Unit, AstraZeneca, Cambridge, UK.
  • Pereira M; Center for Molecular Medicine, Department of Neurology and Clinical Neuroscience, Karolinska Institutet and Karolinska University Hospital, 17176, Stockholm, Sweden.
  • Källback P; Biomolecular Mass Spectrometry Imaging, National Resource for Mass Spectrometry Imaging, Science for Life Laboratory, Department of Pharmaceutical Biosciences, Uppsala University, Box 591, SE-75124, Uppsala, Sweden.
  • Svenningsson P; Center for Molecular Medicine, Department of Neurology and Clinical Neuroscience, Karolinska Institutet and Karolinska University Hospital, 17176, Stockholm, Sweden.
  • Karlgren M; Department of Pharmacy, Uppsala University, BMC, Box 580, Uppsala, SE-751 23, Sweden.
  • Goodwin RJA; Pathology Sciences, Drug Safety and Metabolism, IMED Biotech Unit, AstraZeneca, Cambridge, UK.
  • Andrén PE; Biomolecular Mass Spectrometry Imaging, National Resource for Mass Spectrometry Imaging, Science for Life Laboratory, Department of Pharmaceutical Biosciences, Uppsala University, Box 591, SE-75124, Uppsala, Sweden. Electronic address: per.andren@farmbio.uu.se.
Neuroimage ; 172: 808-816, 2018 05 15.
Article em En | MEDLINE | ID: mdl-29329980
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Propranolol / Permeabilidade Capilar / Barreira Hematoencefálica / Espectrometria de Massas por Ionização por Electrospray / Loperamida Limite: Animals Idioma: En Revista: Neuroimage Assunto da revista: DIAGNOSTICO POR IMAGEM Ano de publicação: 2018 Tipo de documento: Article País de afiliação: Suécia
Texto completo
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Buscar no Google

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Propranolol / Permeabilidade Capilar / Barreira Hematoencefálica / Espectrometria de Massas por Ionização por Electrospray / Loperamida Limite: Animals Idioma: En Revista: Neuroimage Assunto da revista: DIAGNOSTICO POR IMAGEM Ano de publicação: 2018 Tipo de documento: Article País de afiliação: Suécia