Estrogen receptor &#945;- (ER&#945;), but not ERß-signaling, is crucially involved in mechanostimulation of bone fracture healing by whole-body vibration.

Haffner-Luntzer, Melanie; Kovtun, Anna; Lackner, Ina; Mödinger, Yvonne; Hacker, Steffen; Liedert, Astrid; Tuckermann, Jan; Ignatius, Anita

Estrogen receptor α- (ERα), but not ERß-signaling, is crucially involved in mechanostimulation of bone fracture healing by whole-body vibration.

Haffner-Luntzer, Melanie; Kovtun, Anna; Lackner, Ina; Mödinger, Yvonne; Hacker, Steffen; Liedert, Astrid; Tuckermann, Jan; Ignatius, Anita.

Afiliação

Haffner-Luntzer M; Institute of Orthopedic Research and Biomechanics, University Medical Center Ulm, Helmholtzstraße 14, 89081 Ulm, Germany. Electronic address: melanie.haffner-luntzer@uni-ulm.de.
Kovtun A; Institute of Orthopedic Research and Biomechanics, University Medical Center Ulm, Helmholtzstraße 14, 89081 Ulm, Germany.
Lackner I; Institute of Orthopedic Research and Biomechanics, University Medical Center Ulm, Helmholtzstraße 14, 89081 Ulm, Germany.
Mödinger Y; Institute of Orthopedic Research and Biomechanics, University Medical Center Ulm, Helmholtzstraße 14, 89081 Ulm, Germany.
Hacker S; Institute of Orthopedic Research and Biomechanics, University Medical Center Ulm, Helmholtzstraße 14, 89081 Ulm, Germany.
Liedert A; Institute of Orthopedic Research and Biomechanics, University Medical Center Ulm, Helmholtzstraße 14, 89081 Ulm, Germany.
Tuckermann J; Institute of Comparative Molecular Endocrinology, Ulm University, Helmholtzstraße 8, 89081 Ulm, Germany.
Ignatius A; Institute of Orthopedic Research and Biomechanics, University Medical Center Ulm, Helmholtzstraße 14, 89081 Ulm, Germany.

Bone ; 110: 11-20, 2018 05.

Article em En | MEDLINE | ID: mdl-29367057

Assuntos

Receptor alfa de Estrogênio/metabolismo; Receptor beta de Estrogênio/metabolismo; Consolidação da Fratura; Fraturas Ósseas/metabolismo; Vibração; Animais; Fenômenos Biomecânicos; Peso Corporal; Calo Ósseo/metabolismo; Estrogênios/sangue; Feminino; Homozigoto; Camundongos; Camundongos Endogâmicos C57BL; Camundongos Knockout; Camundongos Transgênicos; Tamanho do Órgão; Fraturas por Osteoporose/metabolismo; Ovariectomia; Transdução de Sinais; Útero/patologia

Palavras-chave

Bone formation; Estrogen; Estrogen receptors; Fracture healing; Osteoblasts; Vibration

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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Vibração / Consolidação da Fratura / Receptor alfa de Estrogênio / Receptor beta de Estrogênio / Fraturas Ósseas Limite: Animals Idioma: En Revista: Bone Assunto da revista: METABOLISMO / ORTOPEDIA Ano de publicação: 2018 Tipo de documento: Article

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