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Human IgG lacking effector functions demonstrate lower FcRn-binding and reduced transplacental transport.
Stapleton, Nigel M; Armstrong-Fisher, Sylvia S; Andersen, Jan Terje; van der Schoot, C Ellen; Porter, Charlene; Page, Kenneth R; Falconer, Donald; de Haas, Masja; Williamson, Lorna M; Clark, Michael R; Vidarsson, Gestur; Armour, Kathryn L.
Afiliação
  • Stapleton NM; Department of Experimental Immunohematology, Sanquin Research, and Landsteiner Laboratory, Academic Medical Center, University of Amsterdam, Plesmanlaan 125, Amsterdam, 1066 CX, The Netherlands.
  • Armstrong-Fisher SS; RDI Clinical Transfusion Group, Scottish National Blood Transfusion Service, Foresterhill, Aberdeen, AB25 2ZW, UK; Institute of Medical Sciences, University of Aberdeen, Foresterhill, Aberdeen, AB25 2ZD, UK.
  • Andersen JT; Department of Immunology, Oslo University Hospital Rikshospitalet and University of Oslo, PO Box 4950, Nydalen, Oslo, 0424, Norway; Centre for Immune Regulation and Department of Biosciences, University of Oslo, PO box 1041, Blindern, Oslo, 0316, Norway; Department of Pharmacology, Institute of Clin
  • van der Schoot CE; Department of Experimental Immunohematology, Sanquin Research, and Landsteiner Laboratory, Academic Medical Center, University of Amsterdam, Plesmanlaan 125, Amsterdam, 1066 CX, The Netherlands.
  • Porter C; Immunology Laboratory, Department of Pathology, Aberdeen Royal Infirmary, Aberdeen, AB25 2ZB, UK.
  • Page KR; Institute of Medical Sciences, University of Aberdeen, Foresterhill, Aberdeen, AB25 2ZD, UK.
  • Falconer D; Institute of Medical Sciences, University of Aberdeen, Foresterhill, Aberdeen, AB25 2ZD, UK.
  • de Haas M; Department of Experimental Immunohematology, Sanquin Research, and Landsteiner Laboratory, Academic Medical Center, University of Amsterdam, Plesmanlaan 125, Amsterdam, 1066 CX, The Netherlands.
  • Williamson LM; Department of Haematology, University of Cambridge, UK; NHS Blood and Transplant, Long Road, Cambridge, CB2 2PT, UK.
  • Clark MR; Department of Pathology, University of Cambridge, Tennis Court Road, Cambridge, CB2 1QP, UK.
  • Vidarsson G; Department of Experimental Immunohematology, Sanquin Research, and Landsteiner Laboratory, Academic Medical Center, University of Amsterdam, Plesmanlaan 125, Amsterdam, 1066 CX, The Netherlands. Electronic address: G.Vidarsson@sanquin.nl.
  • Armour KL; Department of Haematology, University of Cambridge, UK; Department of Pathology, University of Cambridge, Tennis Court Road, Cambridge, CB2 1QP, UK.
Mol Immunol ; 95: 1-9, 2018 03.
Article em En | MEDLINE | ID: mdl-29367080
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Placenta / Imunoglobulina G / Receptores Fc / Antígenos de Histocompatibilidade Classe I Tipo de estudo: Prognostic_studies Limite: Female / Humans / Pregnancy Idioma: En Revista: Mol Immunol Ano de publicação: 2018 Tipo de documento: Article País de afiliação: Holanda
Texto completo
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XML
PubMed Links
Buscar no Google

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Placenta / Imunoglobulina G / Receptores Fc / Antígenos de Histocompatibilidade Classe I Tipo de estudo: Prognostic_studies Limite: Female / Humans / Pregnancy Idioma: En Revista: Mol Immunol Ano de publicação: 2018 Tipo de documento: Article País de afiliação: Holanda