Non-contrast enhanced 4D intracranial MR angiography based on pseudo-continuous arterial spin labeling with the keyhole and view-sharing technique.
Magn Reson Med
; 80(2): 719-725, 2018 08.
Article
em En
| MEDLINE
| ID: mdl-29369424
ABSTRACT
PURPOSE:
4D dynamic MR angiography (4D-MRA) using pseudo-continuous arterial spin labeling (pCASL), combined with Keyhole and View-sharing (4D-PACK) for scan acceleration, is introduced. Its validity for arterial inflow dynamics visualization was investigated through comparison with 4D-pCASL and contrast inherent inflow enhanced multiphase angiography (CINEMA).METHODS:
Six healthy volunteers were included in the study. The arterial transit time (ATT) in 4D-PACK was measured at multiple regions in middle cerebral artery (MCA), and Pearson's correlation coefficient with ATT in 4D-pCASL was calculated. The contrast-to-noise ratio (CNR) in 4D-PACK was measured in four MCA segments and compared with that in 4D-pCASL and CINEMA. Arterial visualization in 4D-PACK was assessed qualitatively in patients with moyamoya disease and arteriovenous malformation by comparing with CINEMA.RESULTS:
4D-PACK achieved a 36% scan time reduction compared with 4D-pCASL. The correlation coefficient for ATT measured by 4D-pCASL and 4D-PACK was greater than 0.96. The CNR was significantly higher using 4D-PACK compared with CINEMA in the M4 segment (P < 0.01). In patient examinations, the flow in the collateral artery or draining vein was better visualized in 4D-PACK compared with CINEMA.CONCLUSION:
4D-PACK accelerates 4D-pCASL, shows similar inflow dynamics as 4D-pCASL and shows better peripheral visualization compared with CINEMA. Magn Reson Med 80719-725, 2018. © 2018 International Society for Magnetic Resonance in Medicine.Palavras-chave
Texto completo:
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Base de dados:
MEDLINE
Assunto principal:
Artérias Cerebrais
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Angiografia por Ressonância Magnética
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Imageamento Tridimensional
Limite:
Adult
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Female
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Humans
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Male
Idioma:
En
Revista:
Magn Reson Med
Assunto da revista:
DIAGNOSTICO POR IMAGEM
Ano de publicação:
2018
Tipo de documento:
Article
País de afiliação:
Japão