MDN-0171, a new medermycin analogue from Streptomyces albolongus CA-186053.
Nat Prod Res
; 33(1): 66-73, 2019 Jan.
Article
em En
| MEDLINE
| ID: mdl-29411643
ABSTRACT
A new medermycin derivative, MDN-0171 (1), and two known structurally related compounds, medermycin (2) and antibiotic G15-F (3) were isolated from the acetone extract of culture broths of the marine-derived Streptomyces albolongus strain CA-186053. Their structures were determined using a combination of spectroscopic techniques, including 1D and 2D NMR and electrospray-time of flight mass spectrometry (ESI-TOF MS). Compounds 2 and 3 accounted for the antimicrobial activity (against methicillin-resistant Staphylococcus aureus and Escherichia coli) previously detected in the crude extract of this actinomycete.
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Texto completo:
1
Base de dados:
MEDLINE
Assunto principal:
Streptomyces
Idioma:
En
Revista:
Nat Prod Res
Ano de publicação:
2019
Tipo de documento:
Article
País de afiliação:
Espanha