The role of regulatory T cells in immunopathogenesis and immunotherapy of viral infections.
Infect Genet Evol
; 59: 32-37, 2018 04.
Article
em En
| MEDLINE
| ID: mdl-29413883
ABSTRACT
Two hepatotropic viruses hepatitis C virus (HCV) and hepatitis B virus (HBV) have been considered as the main cause of chronic viral infections. In addition, human immunodeficiency virus (HIV) attacks the immune system by eradication of some white blood cell (T-helper cell). The role of Tregs in HCV, HBV and HIV infections ranges from suppressing antiviral T cell responses to protecting tissues as liver and immune cells from immune mediated injury. In this review, we discuss the influence of regulatory T cells in immunopathology of specific viral infections including HCV, HBV and HIV by focusing on targeting Tregs as novel approach in vaccinology against viral infections.
Palavras-chave
Texto completo:
1
Base de dados:
MEDLINE
Assunto principal:
Viroses
/
Linfócitos T Reguladores
/
Interações Hospedeiro-Patógeno
Limite:
Humans
Idioma:
En
Revista:
Infect Genet Evol
Assunto da revista:
BIOLOGIA
/
DOENCAS TRANSMISSIVEIS
/
GENETICA
Ano de publicação:
2018
Tipo de documento:
Article
País de afiliação:
Irã