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Structure and biophysical characterization of the human full-length neurturin-GFRa2 complex: A role for heparan sulfate in signaling.
Sandmark, Jenny; Dahl, Göran; Öster, Linda; Xu, Bingze; Johansson, Patrik; Akerud, Tomas; Aagaard, Anna; Davidsson, Pia; Bigalke, Janna M; Winzell, Maria Sörhede; Rainey, G Jonah; Roth, Robert G.
Afiliação
  • Sandmark J; From the Departments of Structure, Biophysics and Fragment-based Lead Generation, Discovery Sciences.
  • Dahl G; From the Departments of Structure, Biophysics and Fragment-based Lead Generation, Discovery Sciences.
  • Öster L; From the Departments of Structure, Biophysics and Fragment-based Lead Generation, Discovery Sciences.
  • Xu B; the Division of Medical Inflammation Research, Department of Medical Biochemistry and Biophysics, Karolinska Institutet, Stockholm 17177, Sweden.
  • Johansson P; Discovery Biology, Discovery Sciences, IMED Biotech Unit, AstraZeneca, Gothenburg 43183, Sweden.
  • Akerud T; From the Departments of Structure, Biophysics and Fragment-based Lead Generation, Discovery Sciences.
  • Aagaard A; From the Departments of Structure, Biophysics and Fragment-based Lead Generation, Discovery Sciences.
  • Davidsson P; From the Departments of Structure, Biophysics and Fragment-based Lead Generation, Discovery Sciences.
  • Bigalke JM; Bioscience, Cardiovascular and Metabolic Diseases, and.
  • Winzell MS; From the Departments of Structure, Biophysics and Fragment-based Lead Generation, Discovery Sciences.
  • Rainey GJ; Bioscience, Cardiovascular and Metabolic Diseases, and.
  • Roth RG; the Department of Antibody Discovery and Protein Engineering, MedImmune, Gaithersburg, Maryland 20878, and.
J Biol Chem ; 293(15): 5492-5508, 2018 04 13.
Article em En | MEDLINE | ID: mdl-29414779
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Transdução de Sinais / Complexos Multiproteicos / Neurturina / Receptores de Fator Neurotrófico Derivado de Linhagem de Célula Glial / Heparitina Sulfato Tipo de estudo: Prognostic_studies Limite: Humans Idioma: En Revista: J Biol Chem Ano de publicação: 2018 Tipo de documento: Article
Texto completo
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Buscar no Google

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Transdução de Sinais / Complexos Multiproteicos / Neurturina / Receptores de Fator Neurotrófico Derivado de Linhagem de Célula Glial / Heparitina Sulfato Tipo de estudo: Prognostic_studies Limite: Humans Idioma: En Revista: J Biol Chem Ano de publicação: 2018 Tipo de documento: Article