Both lipopolysaccharide and lipoteichoic acids potently induce anomalous fibrin amyloid formation: assessment with novel Amytracker&#8482; stains.

Pretorius, Etheresia; Page, Martin J; Hendricks, Lisa; Nkosi, Nondumiso B; Benson, Sven R; Kell, Douglas B

Both lipopolysaccharide and lipoteichoic acids potently induce anomalous fibrin amyloid formation: assessment with novel Amytracker™ stains.

Pretorius, Etheresia; Page, Martin J; Hendricks, Lisa; Nkosi, Nondumiso B; Benson, Sven R; Kell, Douglas B.

Afiliação

Pretorius E; Department of Physiological Sciences, Stellenbosch University, Stellenbosch Private Bag X1, Matieland 7602, South Africa resiap@sun.ac.za.
Page MJ; Department of Physiological Sciences, Stellenbosch University, Stellenbosch Private Bag X1, Matieland 7602, South Africa.
Hendricks L; Department of Physiological Sciences, Stellenbosch University, Stellenbosch Private Bag X1, Matieland 7602, South Africa.
Nkosi NB; Department of Physiological Sciences, Stellenbosch University, Stellenbosch Private Bag X1, Matieland 7602, South Africa.
Benson SR; Department of Physiological Sciences, Stellenbosch University, Stellenbosch Private Bag X1, Matieland 7602, South Africa.
Kell DB; Department of Physiological Sciences, Stellenbosch University, Stellenbosch Private Bag X1, Matieland 7602, South Africa dbk@manchester.ac.uk.

J R Soc Interface ; 15(139)2018 02.

Article em En | MEDLINE | ID: mdl-29445039

Assuntos

Amiloide; Coagulação Sanguínea/efeitos dos fármacos; Fibrina; Corantes Fluorescentes; Bactérias Gram-Negativas/química; Lipopolissacarídeos; Ácidos Teicoicos; Amiloide/química; Amiloide/metabolismo; Feminino; Fibrina/química; Fibrina/metabolismo; Corantes Fluorescentes/química; Corantes Fluorescentes/farmacologia; Humanos; Lipopolissacarídeos/química; Lipopolissacarídeos/farmacologia; Masculino; Ácidos Teicoicos/química; Ácidos Teicoicos/farmacologia

Palavras-chave

amyloidogenesis; conjugated oligothiophene dyes; fibrin; iron; lipopolysaccharide; lipoteichoic acids; thioflavin T

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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Ácidos Teicoicos / Coagulação Sanguínea / Fibrina / Lipopolissacarídeos / Corantes Fluorescentes / Bactérias Gram-Negativas / Amiloide Limite: Female / Humans / Male Idioma: En Revista: J R Soc Interface Ano de publicação: 2018 Tipo de documento: Article País de afiliação: África do Sul

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