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Overexpression of BLM promotes DNA damage and increased sensitivity to platinum salts in triple-negative breast and serous ovarian cancers.
Birkbak, N J; Li, Y; Pathania, S; Greene-Colozzi, A; Dreze, M; Bowman-Colin, C; Sztupinszki, Z; Krzystanek, M; Diossy, M; Tung, N; Ryan, P D; Garber, J E; Silver, D P; Iglehart, J D; Wang, Z C; Szuts, D; Szallasi, Z; Richardson, A L.
Afiliação
  • Birkbak NJ; Department of Bio and Health Informatics, Technical University of Denmark, Lyngby, Denmark; Dana-Farber Cancer Institute, Harvard Medical School, Boston, USA.
  • Li Y; Dana-Farber Cancer Institute, Harvard Medical School, Boston, USA.
  • Pathania S; Dana-Farber Cancer Institute, Harvard Medical School, Boston, USA.
  • Greene-Colozzi A; Dana-Farber Cancer Institute, Harvard Medical School, Boston, USA.
  • Dreze M; Dana-Farber Cancer Institute, Harvard Medical School, Boston, USA.
  • Bowman-Colin C; Dana-Farber Cancer Institute, Harvard Medical School, Boston, USA.
  • Sztupinszki Z; Department of Bio and Health Informatics, Technical University of Denmark, Lyngby, Denmark.
  • Krzystanek M; Department of Bio and Health Informatics, Technical University of Denmark, Lyngby, Denmark.
  • Diossy M; Department of Bio and Health Informatics, Technical University of Denmark, Lyngby, Denmark.
  • Tung N; Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, USA.
  • Ryan PD; Texas Oncology, The Woodlands, USA.
  • Garber JE; Dana-Farber Cancer Institute, Harvard Medical School, Boston, USA.
  • Silver DP; Dana-Farber Cancer Institute, Harvard Medical School, Boston, USA; Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, USA.
  • Iglehart JD; Dana-Farber Cancer Institute, Harvard Medical School, Boston, USA; Brigham and Women's Hospital, Harvard Medical School, Boston, USA.
  • Wang ZC; Dana-Farber Cancer Institute, Harvard Medical School, Boston, USA; Brigham and Women's Hospital, Harvard Medical School, Boston, USA.
  • Szuts D; Institute of Enzymolog, Research Center for Natural Sciences, Hungarian Academy of Sciences, Budapest, Hungary.
  • Szallasi Z; Department of Bio and Health Informatics, Technical University of Denmark, Lyngby, Denmark; Computational Health Informatics Program (CHIP) Boston Children's Hospital Harvard Medical School, Boston, USA. Electronic address: Zoltan.szallasi@childrens.harvard.edu.
  • Richardson AL; Dana-Farber Cancer Institute, Harvard Medical School, Boston, USA; Brigham and Women's Hospital, Harvard Medical School, Boston, USA. Electronic address: aricha58@jhmi.edu.
Ann Oncol ; 29(4): 903-909, 2018 04 01.
Article em En | MEDLINE | ID: mdl-29452344

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Neoplasias Ovarianas / Dano ao DNA / Compostos de Platina / RecQ Helicases / Neoplasias de Mama Triplo Negativas / Antineoplásicos Tipo de estudo: Diagnostic_studies Limite: Female / Humans Idioma: En Revista: Ann Oncol Assunto da revista: NEOPLASIAS Ano de publicação: 2018 Tipo de documento: Article País de afiliação: Estados Unidos

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Neoplasias Ovarianas / Dano ao DNA / Compostos de Platina / RecQ Helicases / Neoplasias de Mama Triplo Negativas / Antineoplásicos Tipo de estudo: Diagnostic_studies Limite: Female / Humans Idioma: En Revista: Ann Oncol Assunto da revista: NEOPLASIAS Ano de publicação: 2018 Tipo de documento: Article País de afiliação: Estados Unidos