Impact of target interactions on small-molecule drug disposition: an overlooked area.

van Waterschoot, Robert A B; Parrott, Neil J; Olivares-Morales, Andrés; Lavé, Thierry; Rowland, Malcolm; Smith, Dennis A

van Waterschoot, Robert A B; Parrott, Neil J; Olivares-Morales, Andrés; Lavé, Thierry; Rowland, Malcolm; Smith, Dennis A.

Afiliação

van Waterschoot RAB; Roche Pharmaceutical Research and Early Development, Pharmaceutical Sciences, Roche Innovation Center Basel, Switzerland.
Parrott NJ; Roche Pharmaceutical Research and Early Development, Pharmaceutical Sciences, Roche Innovation Center Basel, Switzerland.
Olivares-Morales A; Roche Pharmaceutical Research and Early Development, Pharmaceutical Sciences, Roche Innovation Center Basel, Switzerland.
Lavé T; Roche Pharmaceutical Research and Early Development, Pharmaceutical Sciences, Roche Innovation Center Basel, Switzerland.
Rowland M; Centre for Applied Pharmacokinetic Research, Manchester Pharmacy School, University of Manchester, Manchester, UK.
Smith DA; Department of Chemistry, University of Capetown, Capetown, South Africa.

Nat Rev Drug Discov ; 17(4): 299, 2018 04.

Article em En | MEDLINE | ID: mdl-29472637

Assuntos

Sistemas de Liberação de Medicamentos; Distribuição Tecidual

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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Sistemas de Liberação de Medicamentos Idioma: En Revista: Nat Rev Drug Discov Assunto da revista: FARMACOLOGIA / TERAPIA POR MEDICAMENTOS Ano de publicação: 2018 Tipo de documento: Article País de afiliação: Suíça

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