Epidemiology and seasonality of acute respiratory infections in hospitalized children over four consecutive years (2012-2016).
J Clin Virol
; 102: 27-31, 2018 05.
Article
em En
| MEDLINE
| ID: mdl-29477833
ABSTRACT
BACKGROUND:
Acute respiratory infections are a principal cause of illness and mortality especially in young children worldwide.OBJECTIVES:
To study the epidemiology and seasonality of viral respiratory infections in hospitalized children (under the age of 16) between September 2012 and August 2016. STUDYDESIGN:
Nasopharyngeal swabs or aspirates were collected from 3199 symptomatic patients and then screened with a routine multiplex PCR assay.RESULTS:
Respiratory viruses were detected for 1624 (50.8%) of the 3199 children in the study population. Of these, 210 (13.3%) were positive for two viruses, 28 (1.7%) were positive for three, and 3 (0.2%) were positive for four. The viral profile varied with age. Some viruses were significantly more frequent in children under the age of 1 month (such as human respiratory syncytial virus (pâ¯<â¯0.0001)), whereas others were significantly more frequent in children over that age (such as influenza viruses (pâ¯<â¯0.0001) and adenoviruses (pâ¯=â¯.0006)). The distribution of viruses is variable over the year depending on the species. However, the atmospheric temperature was rarely found to be a limiting factor in the circulation of respiratory viruses.CONCLUSIONS:
our results constitute a detailed description of the distribution of respiratory viruses among hospitalized children over four consecutive years. Our data notably highlight the persistence of non-enveloped viruses and some enveloped viruses throughout the year-regardless of temperature variations.Palavras-chave
Texto completo:
1
Base de dados:
MEDLINE
Assunto principal:
Infecções Respiratórias
/
Estações do Ano
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Vírus
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Hospitalização
Tipo de estudo:
Observational_studies
/
Risk_factors_studies
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Screening_studies
Limite:
Adolescent
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Child
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Child, preschool
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Humans
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Infant
/
Newborn
País/Região como assunto:
Europa
Idioma:
En
Revista:
J Clin Virol
Assunto da revista:
VIROLOGIA
Ano de publicação:
2018
Tipo de documento:
Article
País de afiliação:
França