From Chemotherapy to Combined Targeted Therapeutics: <i>In Vitro</i> and <i>in Vivo</i> Models to Decipher Intra-tumor Heterogeneity.

Gambara, Guido; Gaebler, Manuela; Keilholz, Ulrich; Regenbrecht, Christian R A; Silvestri, Alessandra

From Chemotherapy to Combined Targeted Therapeutics: In Vitro and in Vivo Models to Decipher Intra-tumor Heterogeneity.

Gambara, Guido; Gaebler, Manuela; Keilholz, Ulrich; Regenbrecht, Christian R A; Silvestri, Alessandra.

Afiliação

Gambara G; Charité Comprehensive Cancer Center, Charité - Universitätsmedizin, Berlin, Germany.
Gaebler M; German Cancer Consortium (DKTK), German Cancer Research Center (DKFZ), Heidelberg, Germany.
Keilholz U; Department of Interdisciplinary Oncology, HELIOS Klinikum Berlin-Buch GmbH, Berlin, Germany.
Regenbrecht CRA; Charité Comprehensive Cancer Center, Charité - Universitätsmedizin, Berlin, Germany.
Silvestri A; German Cancer Consortium (DKTK), German Cancer Research Center (DKFZ), Heidelberg, Germany.

Front Pharmacol ; 9: 77, 2018.

Article em En | MEDLINE | ID: mdl-29491834

Palavras-chave

PD3D cell culture; PDX models; cancer models; cancer stem cells; organoids; tumor evolution; tumor heterogeneity; tumor microenvironment

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Texto completo: 1 Base de dados: MEDLINE Idioma: En Revista: Front Pharmacol Ano de publicação: 2018 Tipo de documento: Article País de afiliação: Alemanha

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Texto completo: 1 Base de dados: MEDLINE Idioma: En Revista: Front Pharmacol Ano de publicação: 2018 Tipo de documento: Article País de afiliação: Alemanha