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Dynamic Regulation of Long-Chain Fatty Acid Oxidation by a Noncanonical Interaction between the MCL-1 BH3 Helix and VLCAD.
Escudero, Silvia; Zaganjor, Elma; Lee, Susan; Mill, Christopher P; Morgan, Ann M; Crawford, Emily B; Chen, Jiahao; Wales, Thomas E; Mourtada, Rida; Luccarelli, James; Bird, Gregory H; Steidl, Ulrich; Engen, John R; Haigis, Marcia C; Opferman, Joseph T; Walensky, Loren D.
Afiliação
  • Escudero S; Department of Pediatric Oncology and the Linde Program in Cancer Chemical Biology, Dana-Farber Cancer Institute, Boston, MA 02215, USA.
  • Zaganjor E; Department of Cell Biology, Harvard Medical School, Boston, MA 02115, USA.
  • Lee S; Department of Pediatric Oncology and the Linde Program in Cancer Chemical Biology, Dana-Farber Cancer Institute, Boston, MA 02215, USA.
  • Mill CP; Department of Cell and Molecular Biology, St. Jude Children's Research Hospital, Memphis, TN 38105, USA.
  • Morgan AM; Department of Pediatric Oncology and the Linde Program in Cancer Chemical Biology, Dana-Farber Cancer Institute, Boston, MA 02215, USA.
  • Crawford EB; Department of Pediatric Oncology and the Linde Program in Cancer Chemical Biology, Dana-Farber Cancer Institute, Boston, MA 02215, USA.
  • Chen J; Departments of Medicine and Cell Biology, Albert Einstein College of Medicine, Bronx, NY 10461, USA.
  • Wales TE; Department of Chemistry and Chemical Biology, Northeastern University, Boston, MA 02115, USA.
  • Mourtada R; Department of Pediatric Oncology and the Linde Program in Cancer Chemical Biology, Dana-Farber Cancer Institute, Boston, MA 02215, USA.
  • Luccarelli J; Department of Pediatric Oncology and the Linde Program in Cancer Chemical Biology, Dana-Farber Cancer Institute, Boston, MA 02215, USA.
  • Bird GH; Department of Pediatric Oncology and the Linde Program in Cancer Chemical Biology, Dana-Farber Cancer Institute, Boston, MA 02215, USA.
  • Steidl U; Departments of Medicine and Cell Biology, Albert Einstein College of Medicine, Bronx, NY 10461, USA.
  • Engen JR; Department of Chemistry and Chemical Biology, Northeastern University, Boston, MA 02115, USA.
  • Haigis MC; Department of Cell Biology, Harvard Medical School, Boston, MA 02115, USA.
  • Opferman JT; Department of Cell and Molecular Biology, St. Jude Children's Research Hospital, Memphis, TN 38105, USA. Electronic address: joseph.opferman@stjude.org.
  • Walensky LD; Department of Pediatric Oncology and the Linde Program in Cancer Chemical Biology, Dana-Farber Cancer Institute, Boston, MA 02215, USA. Electronic address: loren_walensky@dfci.harvard.edu.
Mol Cell ; 69(5): 729-743.e7, 2018 03 01.
Article em En | MEDLINE | ID: mdl-29499131
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Ácido Palmítico / Acil-CoA Desidrogenase de Cadeia Longa / Metabolismo dos Lipídeos / Proteína de Sequência 1 de Leucemia de Células Mieloides Limite: Animals Idioma: En Revista: Mol Cell Assunto da revista: BIOLOGIA MOLECULAR Ano de publicação: 2018 Tipo de documento: Article País de afiliação: Estados Unidos
Texto completo
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Ácido Palmítico / Acil-CoA Desidrogenase de Cadeia Longa / Metabolismo dos Lipídeos / Proteína de Sequência 1 de Leucemia de Células Mieloides Limite: Animals Idioma: En Revista: Mol Cell Assunto da revista: BIOLOGIA MOLECULAR Ano de publicação: 2018 Tipo de documento: Article País de afiliação: Estados Unidos