MIRA: an R package for DNA methylation-based inference of regulatory activity.
Bioinformatics
; 34(15): 2649-2650, 2018 08 01.
Article
em En
| MEDLINE
| ID: mdl-29506020
ABSTRACT
Summary:
DNA methylation contains information about the regulatory state of the cell. MIRA aggregates genome-scale DNA methylation data into a DNA methylation profile for a given region set with shared biological annotation. Using this profile, MIRA infers and scores the collective regulatory activity for the region set. MIRA facilitates regulatory analysis in situations where classical regulatory assays would be difficult and allows public sources of region sets to be leveraged for novel insight into the regulatory state of DNA methylation datasets. Availability and implementation http//bioconductor.org/packages/MIRA.
Texto completo:
1
Base de dados:
MEDLINE
Assunto principal:
Software
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Análise de Sequência de DNA
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Metilação de DNA
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Epigenômica
Idioma:
En
Revista:
Bioinformatics
Assunto da revista:
INFORMATICA MEDICA
Ano de publicação:
2018
Tipo de documento:
Article
País de afiliação:
Estados Unidos