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Generation of iPSCs carrying a common LRRK2 risk allele for in vitro modeling of idiopathic Parkinson's disease.
Marrone, Lara; Bus, Christine; Schöndorf, David; Fitzgerald, Julia Catherine; Kübler, Manuela; Schmid, Benjamin; Reinhardt, Peter; Reinhardt, Lydia; Deleidi, Michela; Levin, Tanya; Meixner, Andrea; Klink, Barbara; Glatza, Michael; Gloeckner, Christian Johannes; Gasser, Thomas; Sterneckert, Jared.
Afiliação
  • Marrone L; DFG-Center for Regenerative Therapies Technische Universität Dresden (CRTD), Dresden, Germany.
  • Bus C; Department of Neurodegenerative Diseases, Centre of Neurology and Hertie-Institute for Clinical Brain Research, University of Tübingen, Tübingen, Germany.
  • Schöndorf D; German Center for Neurodegenerative Diseases (DZNE), Tübingen, Germany.
  • Fitzgerald JC; Department of Neurodegenerative Diseases, Centre of Neurology and Hertie-Institute for Clinical Brain Research, University of Tübingen, Tübingen, Germany.
  • Kübler M; German Center for Neurodegenerative Diseases (DZNE), Tübingen, Germany.
  • Schmid B; Department of Neurodegenerative Diseases, Centre of Neurology and Hertie-Institute for Clinical Brain Research, University of Tübingen, Tübingen, Germany.
  • Reinhardt P; German Center for Neurodegenerative Diseases (DZNE), Tübingen, Germany.
  • Reinhardt L; Department of Neurodegenerative Diseases, Centre of Neurology and Hertie-Institute for Clinical Brain Research, University of Tübingen, Tübingen, Germany.
  • Deleidi M; German Center for Neurodegenerative Diseases (DZNE), Tübingen, Germany.
  • Levin T; Department of Neurodegenerative Diseases, Centre of Neurology and Hertie-Institute for Clinical Brain Research, University of Tübingen, Tübingen, Germany.
  • Meixner A; DFG-Center for Regenerative Therapies Technische Universität Dresden (CRTD), Dresden, Germany.
  • Klink B; DFG-Center for Regenerative Therapies Technische Universität Dresden (CRTD), Dresden, Germany.
  • Glatza M; Max Planck Institute for Molecular Biomedicine, Münster, Germany.
  • Gloeckner CJ; Department of Neurodegenerative Diseases, Centre of Neurology and Hertie-Institute for Clinical Brain Research, University of Tübingen, Tübingen, Germany.
  • Gasser T; German Center for Neurodegenerative Diseases (DZNE), Tübingen, Germany.
  • Sterneckert J; DFG-Center for Regenerative Therapies Technische Universität Dresden (CRTD), Dresden, Germany.
PLoS One ; 13(3): e0192497, 2018.
Article em En | MEDLINE | ID: mdl-29513666
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Doença de Parkinson / Polimorfismo de Nucleotídeo Único / Células-Tronco Pluripotentes Induzidas / Serina-Treonina Proteína Quinase-2 com Repetições Ricas em Leucina Tipo de estudo: Etiology_studies / Prognostic_studies / Risk_factors_studies Limite: Aged / Female / Humans / Male / Middle aged Idioma: En Revista: PLoS One Assunto da revista: CIENCIA / MEDICINA Ano de publicação: 2018 Tipo de documento: Article País de afiliação: Alemanha
Texto completo
Imprimir
XML
PubMed Links
Buscar no Google

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Doença de Parkinson / Polimorfismo de Nucleotídeo Único / Células-Tronco Pluripotentes Induzidas / Serina-Treonina Proteína Quinase-2 com Repetições Ricas em Leucina Tipo de estudo: Etiology_studies / Prognostic_studies / Risk_factors_studies Limite: Aged / Female / Humans / Male / Middle aged Idioma: En Revista: PLoS One Assunto da revista: CIENCIA / MEDICINA Ano de publicação: 2018 Tipo de documento: Article País de afiliação: Alemanha