A Multicenter Retrospective Review of Pediatric Leydig Cell Tumor of the Testis.
J Pediatr Hematol Oncol
; 41(1): 74-76, 2019 01.
Article
em En
| MEDLINE
| ID: mdl-29554024
ABSTRACT
Leydig cell tumors (LCTs) are rare tumors arising from testosterone-producing Leydig cells. Although LCTs are usually benign, malignancy has been reported in 10% of cases in adults, and local recurrence or metachronous tumors of the contralateral testis have been described. Radical orchiectomy is the current standard of care. We report on 12 children with LCT at 3 institutions between 2000 and 2016. Presenting symptoms included precocious puberty, palpable testicular mass, and scrotal swelling. Radical orchiectomy was performed in 9 patients. Three patients were treated with enucleation. All patients were alive at last follow-up without evidence of local recurrence or metastasis.
Texto completo:
1
Base de dados:
MEDLINE
Assunto principal:
Puberdade Precoce
/
Neoplasias Testiculares
/
Orquiectomia
/
Tumor de Células de Leydig
Tipo de estudo:
Diagnostic_studies
/
Observational_studies
/
Prognostic_studies
Limite:
Adolescent
/
Child
/
Child, preschool
/
Humans
/
Male
Idioma:
En
Revista:
J Pediatr Hematol Oncol
Assunto da revista:
HEMATOLOGIA
/
NEOPLASIAS
/
PEDIATRIA
Ano de publicação:
2019
Tipo de documento:
Article