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Discovery of Small-Molecule Antagonists of the H3K9me3 Binding to UHRF1 Tandem Tudor Domain.
Senisterra, Guillermo; Zhu, Hugh Y; Luo, Xiao; Zhang, Hailong; Xun, Guoliang; Lu, Chunliang; Xiao, Wen; Hajian, Taraneh; Loppnau, Peter; Chau, Irene; Li, Fengling; Allali-Hassani, Abdellah; Atadja, Peter; Oyang, Counde; Li, En; Brown, Peter J; Arrowsmith, Cheryl H; Zhao, Kehao; Yu, Zhengtian; Vedadi, Masoud.
Afiliação
  • Senisterra G; 1 Structural Genomics Consortium, University of Toronto, Toronto, ON, Canada.
  • Zhu HY; 2 Novartis Institutes for BioMedical Research (China), Pudong, Shanghai, China.
  • Luo X; 2 Novartis Institutes for BioMedical Research (China), Pudong, Shanghai, China.
  • Zhang H; 2 Novartis Institutes for BioMedical Research (China), Pudong, Shanghai, China.
  • Xun G; 2 Novartis Institutes for BioMedical Research (China), Pudong, Shanghai, China.
  • Lu C; 2 Novartis Institutes for BioMedical Research (China), Pudong, Shanghai, China.
  • Xiao W; 2 Novartis Institutes for BioMedical Research (China), Pudong, Shanghai, China.
  • Hajian T; 1 Structural Genomics Consortium, University of Toronto, Toronto, ON, Canada.
  • Loppnau P; 1 Structural Genomics Consortium, University of Toronto, Toronto, ON, Canada.
  • Chau I; 1 Structural Genomics Consortium, University of Toronto, Toronto, ON, Canada.
  • Li F; 1 Structural Genomics Consortium, University of Toronto, Toronto, ON, Canada.
  • Allali-Hassani A; 1 Structural Genomics Consortium, University of Toronto, Toronto, ON, Canada.
  • Atadja P; 2 Novartis Institutes for BioMedical Research (China), Pudong, Shanghai, China.
  • Oyang C; 2 Novartis Institutes for BioMedical Research (China), Pudong, Shanghai, China.
  • Li E; 2 Novartis Institutes for BioMedical Research (China), Pudong, Shanghai, China.
  • Brown PJ; 1 Structural Genomics Consortium, University of Toronto, Toronto, ON, Canada.
  • Arrowsmith CH; 1 Structural Genomics Consortium, University of Toronto, Toronto, ON, Canada.
  • Zhao K; 3 Princess Margaret Cancer Centre and Department of Medical Biophysics, University of Toronto, Toronto, ON, Canada.
  • Yu Z; 2 Novartis Institutes for BioMedical Research (China), Pudong, Shanghai, China.
  • Vedadi M; 4 School of Pharmacy, Key Laboratory of Molecular Pharmacology and Drug Evaluation (Yantai University), Ministry of Education, Collaborative Innovation Center of Advanced Drug Delivery System and Biotech Drugs in Universities of Shandong, Yantai University, Yantai, China.
SLAS Discov ; 23(9): 930-940, 2018 10.
Article em En | MEDLINE | ID: mdl-29562800
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Ligação Proteica / Histonas / Proteínas Estimuladoras de Ligação a CCAAT / Descoberta de Drogas / Domínio Tudor Limite: Humans Idioma: En Revista: SLAS Discov Ano de publicação: 2018 Tipo de documento: Article País de afiliação: Canadá
Texto completo
Imprimir
XML
PubMed Links
Buscar no Google

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Ligação Proteica / Histonas / Proteínas Estimuladoras de Ligação a CCAAT / Descoberta de Drogas / Domínio Tudor Limite: Humans Idioma: En Revista: SLAS Discov Ano de publicação: 2018 Tipo de documento: Article País de afiliação: Canadá