Novel biomarker, phosphorylated T-LAK cell-originated protein kinase (p-TOPK) can predict outcome in primary central nervous system lymphoma.

Koh, Masaki; Hayakawa, Yumiko; Akai, Takuya; Hayashi, Tomohide; Tomita, Takahiro; Nagai, Shoichi; Kuroda, Satoshi

Koh, Masaki; Hayakawa, Yumiko; Akai, Takuya; Hayashi, Tomohide; Tomita, Takahiro; Nagai, Shoichi; Kuroda, Satoshi.

Afiliação

Koh M; Department of Neurosurgery, Graduate School of Medicine and Pharmaceutical Science, University of Toyama, Toyama, Japan.
Hayakawa Y; Department of Neurosurgery, Graduate School of Medicine and Pharmaceutical Science, University of Toyama, Toyama, Japan.
Akai T; Department of Neurosurgery, Graduate School of Medicine and Pharmaceutical Science, University of Toyama, Toyama, Japan.
Hayashi T; Department of Neurosurgery, Graduate School of Medicine and Pharmaceutical Science, University of Toyama, Toyama, Japan.
Tomita T; Department of Neurosurgery, Graduate School of Medicine and Pharmaceutical Science, University of Toyama, Toyama, Japan.
Nagai S; Department of Neurosurgery, Graduate School of Medicine and Pharmaceutical Science, University of Toyama, Toyama, Japan.
Kuroda S; Department of Neurosurgery, Graduate School of Medicine and Pharmaceutical Science, University of Toyama, Toyama, Japan.

Neuropathology ; 38(3): 228-236, 2018 Jun.

Article em En | MEDLINE | ID: mdl-29575092

Assuntos

Neoplasias do Sistema Nervoso Central/diagnóstico; Linfoma/diagnóstico; Quinases de Proteína Quinase Ativadas por Mitógeno/metabolismo; Idoso; Idoso de 80 Anos ou mais; Biomarcadores Tumorais/metabolismo; Neoplasias do Sistema Nervoso Central/metabolismo; Neoplasias do Sistema Nervoso Central/terapia; Intervalo Livre de Doença; Feminino; Humanos; Linfoma/metabolismo; Masculino; Pessoa de Meia-Idade; Fosforilação

Palavras-chave

T-LAK cell-originated protein kinase; mitosis; phosphorylation; primary central nervous system lymphoma; prognosis

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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Neoplasias do Sistema Nervoso Central / Quinases de Proteína Quinase Ativadas por Mitógeno / Linfoma Tipo de estudo: Prognostic_studies / Risk_factors_studies Limite: Aged / Aged80 / Female / Humans / Male / Middle aged Idioma: En Revista: Neuropathology Assunto da revista: NEUROLOGIA / PATOLOGIA Ano de publicação: 2018 Tipo de documento: Article País de afiliação: Japão

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