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Alternative splice variants of DCLK1 mark cancer stem cells, promote self-renewal and drug-resistance, and can be targeted to inhibit tumorigenesis in kidney cancer.
Ge, Yang; Weygant, Nathaniel; Qu, Dongfeng; May, Randal; Berry, William L; Yao, Jiannan; Chandrakesan, Parthasarathy; Zheng, Wei; Zhao, Lichao; Zhao, Karena L; Drake, Michael; Vega, Kenneth J; Bronze, Michael S; Tomasek, James J; An, Guangyu; Houchen, Courtney W.
Afiliação
  • Ge Y; Department of Oncology, Beijing Chao-Yang Hospital, Capital Medical University, Beijing, China.
  • Weygant N; Department of Medicine, The University of Oklahoma Health Sciences Center, Oklahoma City, OK.
  • Qu D; COARE Biotechnology Inc., Oklahoma City, OK.
  • May R; Department of Medicine, The University of Oklahoma Health Sciences Center, Oklahoma City, OK.
  • Berry WL; COARE Biotechnology Inc., Oklahoma City, OK.
  • Yao J; The Peggy and Charles Stephenson Cancer Center, Oklahoma City, OK.
  • Chandrakesan P; United States Department of Veterans Affairs Medical Center, Oklahoma City, OK.
  • Zheng W; Department of Medicine, The University of Oklahoma Health Sciences Center, Oklahoma City, OK.
  • Zhao L; COARE Biotechnology Inc., Oklahoma City, OK.
  • Zhao KL; United States Department of Veterans Affairs Medical Center, Oklahoma City, OK.
  • Drake M; Department of Cell Biology, The University of Oklahoma Health Sciences Center, Oklahoma City, OK.
  • Vega KJ; Department of Oncology, Beijing Chao-Yang Hospital, Capital Medical University, Beijing, China.
  • Bronze MS; Department of Medicine, The University of Oklahoma Health Sciences Center, Oklahoma City, OK.
  • Tomasek JJ; COARE Biotechnology Inc., Oklahoma City, OK.
  • An G; The Peggy and Charles Stephenson Cancer Center, Oklahoma City, OK.
  • Houchen CW; Department of Pathology, The University of Oklahoma Health Sciences Center, Oklahoma City, OK.
Int J Cancer ; 143(5): 1162-1175, 2018 09 01.
Article em En | MEDLINE | ID: mdl-29577277
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Células-Tronco Neoplásicas / Carcinoma de Células Renais / Transformação Celular Neoplásica / Proteínas Serina-Treonina Quinases / Processamento Alternativo / Resistencia a Medicamentos Antineoplásicos / Peptídeos e Proteínas de Sinalização Intracelular / Neoplasias Renais Tipo de estudo: Observational_studies / Prognostic_studies / Risk_factors_studies Limite: Animals / Humans / Male Idioma: En Revista: Int J Cancer Ano de publicação: 2018 Tipo de documento: Article País de afiliação: China
Texto completo
Imprimir
XML
PubMed Links
Buscar no Google

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Células-Tronco Neoplásicas / Carcinoma de Células Renais / Transformação Celular Neoplásica / Proteínas Serina-Treonina Quinases / Processamento Alternativo / Resistencia a Medicamentos Antineoplásicos / Peptídeos e Proteínas de Sinalização Intracelular / Neoplasias Renais Tipo de estudo: Observational_studies / Prognostic_studies / Risk_factors_studies Limite: Animals / Humans / Male Idioma: En Revista: Int J Cancer Ano de publicação: 2018 Tipo de documento: Article País de afiliação: China