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Identification of Pik3ca Mutation as a Genetic Driver of Prostate Cancer That Cooperates with Pten Loss to Accelerate Progression and Castration-Resistant Growth.
Pearson, Helen B; Li, Jason; Meniel, Valerie S; Fennell, Christina M; Waring, Paul; Montgomery, Karen G; Rebello, Richard J; Macpherson, Arthi A; Koushyar, Sarah; Furic, Luc; Cullinane, Carleen; Clarkson, Richard W; Smalley, Matthew J; Simpson, Kaylene J; Phesse, Toby J; Shepherd, Peter R; Humbert, Patrick O; Sansom, Owen J; Phillips, Wayne A.
Afiliação
  • Pearson HB; Peter MacCallum Cancer Centre, Melbourne, Victoria, Australia. PearsonH2@cardiff.ac.uk.
  • Li J; The Sir Peter MacCallum Department of Oncology, the University of Melbourne, Parkville, Victoria, Australia.
  • Meniel VS; European Cancer Stem Cell Research Institute, Haydn Ellis Building, Cardiff University, Cardiff, United Kingdom.
  • Fennell CM; Peter MacCallum Cancer Centre, Melbourne, Victoria, Australia.
  • Waring P; The Sir Peter MacCallum Department of Oncology, the University of Melbourne, Parkville, Victoria, Australia.
  • Montgomery KG; European Cancer Stem Cell Research Institute, Haydn Ellis Building, Cardiff University, Cardiff, United Kingdom.
  • Rebello RJ; Peter MacCallum Cancer Centre, Melbourne, Victoria, Australia.
  • Macpherson AA; Department of Pathology, the University of Melbourne, Parkville, Victoria, Australia.
  • Koushyar S; Peter MacCallum Cancer Centre, Melbourne, Victoria, Australia.
  • Furic L; Peter MacCallum Cancer Centre, Melbourne, Victoria, Australia.
  • Cullinane C; Cancer Program, Biomedicine Discovery Institute and Department of Anatomy and Developmental Biology, Monash University, Clayton, Victoria, Australia.
  • Clarkson RW; Victorian Centre for Functional Genomics, ACRF RPPA Platform, Peter MacCallum Cancer Centre, Melbourne, Victoria, Australia.
  • Smalley MJ; European Cancer Stem Cell Research Institute, Haydn Ellis Building, Cardiff University, Cardiff, United Kingdom.
  • Simpson KJ; Peter MacCallum Cancer Centre, Melbourne, Victoria, Australia.
  • Phesse TJ; The Sir Peter MacCallum Department of Oncology, the University of Melbourne, Parkville, Victoria, Australia.
  • Shepherd PR; Cancer Program, Biomedicine Discovery Institute and Department of Anatomy and Developmental Biology, Monash University, Clayton, Victoria, Australia.
  • Humbert PO; Peter MacCallum Cancer Centre, Melbourne, Victoria, Australia.
  • Sansom OJ; The Sir Peter MacCallum Department of Oncology, the University of Melbourne, Parkville, Victoria, Australia.
  • Phillips WA; European Cancer Stem Cell Research Institute, Haydn Ellis Building, Cardiff University, Cardiff, United Kingdom.
Cancer Discov ; 8(6): 764-779, 2018 06.
Article em En | MEDLINE | ID: mdl-29581176
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: PTEN Fosfo-Hidrolase / Classe I de Fosfatidilinositol 3-Quinases / Neoplasias de Próstata Resistentes à Castração / Mutação Tipo de estudo: Diagnostic_studies / Prognostic_studies Limite: Animals / Humans / Male Idioma: En Revista: Cancer Discov Ano de publicação: 2018 Tipo de documento: Article País de afiliação: Austrália
Texto completo
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XML
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: PTEN Fosfo-Hidrolase / Classe I de Fosfatidilinositol 3-Quinases / Neoplasias de Próstata Resistentes à Castração / Mutação Tipo de estudo: Diagnostic_studies / Prognostic_studies Limite: Animals / Humans / Male Idioma: En Revista: Cancer Discov Ano de publicação: 2018 Tipo de documento: Article País de afiliação: Austrália