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A single-cell hematopoietic landscape resolves 8 lineage trajectories and defects in Kit mutant mice.
Dahlin, Joakim S; Hamey, Fiona K; Pijuan-Sala, Blanca; Shepherd, Mairi; Lau, Winnie W Y; Nestorowa, Sonia; Weinreb, Caleb; Wolock, Samuel; Hannah, Rebecca; Diamanti, Evangelia; Kent, David G; Göttgens, Berthold; Wilson, Nicola K.
Afiliação
  • Dahlin JS; Department of Haematology, University of Cambridge, Cambridge Institute for Medical Research and Wellcome-Medical Research Council Cambridge Stem Cell Institute, Cambridge, United Kingdom.
  • Hamey FK; Department of Medicine, Karolinska Institutet and Karolinska University Hospital, Stockholm, Sweden.
  • Pijuan-Sala B; Department of Haematology, University of Cambridge, Cambridge Institute for Medical Research and Wellcome-Medical Research Council Cambridge Stem Cell Institute, Cambridge, United Kingdom.
  • Shepherd M; Department of Haematology, University of Cambridge, Cambridge Institute for Medical Research and Wellcome-Medical Research Council Cambridge Stem Cell Institute, Cambridge, United Kingdom.
  • Lau WWY; Department of Haematology, University of Cambridge, Wellcome-Medical Research Council Cambridge Stem Cell Institute, Cambridge, United Kingdom; and.
  • Nestorowa S; Department of Haematology, University of Cambridge, Cambridge Institute for Medical Research and Wellcome-Medical Research Council Cambridge Stem Cell Institute, Cambridge, United Kingdom.
  • Weinreb C; Department of Haematology, University of Cambridge, Cambridge Institute for Medical Research and Wellcome-Medical Research Council Cambridge Stem Cell Institute, Cambridge, United Kingdom.
  • Wolock S; Department of Systems Biology, Harvard Medical School, Boston, MA.
  • Hannah R; Department of Systems Biology, Harvard Medical School, Boston, MA.
  • Diamanti E; Department of Haematology, University of Cambridge, Cambridge Institute for Medical Research and Wellcome-Medical Research Council Cambridge Stem Cell Institute, Cambridge, United Kingdom.
  • Kent DG; Department of Haematology, University of Cambridge, Cambridge Institute for Medical Research and Wellcome-Medical Research Council Cambridge Stem Cell Institute, Cambridge, United Kingdom.
  • Göttgens B; Department of Haematology, University of Cambridge, Wellcome-Medical Research Council Cambridge Stem Cell Institute, Cambridge, United Kingdom; and.
  • Wilson NK; Department of Haematology, University of Cambridge, Cambridge Institute for Medical Research and Wellcome-Medical Research Council Cambridge Stem Cell Institute, Cambridge, United Kingdom.
Blood ; 131(21): e1-e11, 2018 05 24.
Article em En | MEDLINE | ID: mdl-29588278

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Células-Tronco Hematopoéticas / Diferenciação Celular / Proteínas Proto-Oncogênicas c-kit / Linhagem da Célula / Mutação Tipo de estudo: Prognostic_studies Limite: Animals Idioma: En Revista: Blood Ano de publicação: 2018 Tipo de documento: Article País de afiliação: Reino Unido

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Células-Tronco Hematopoéticas / Diferenciação Celular / Proteínas Proto-Oncogênicas c-kit / Linhagem da Célula / Mutação Tipo de estudo: Prognostic_studies Limite: Animals Idioma: En Revista: Blood Ano de publicação: 2018 Tipo de documento: Article País de afiliação: Reino Unido