Blast Exposure Disrupts the Tonotopic Frequency Map in the Primary Auditory Cortex.
Neuroscience
; 379: 428-434, 2018 05 21.
Article
em En
| MEDLINE
| ID: mdl-29625214
ABSTRACT
Blast exposure can cause various auditory disorders including tinnitus, hyperacusis, and other central auditory processing disorders. While this is suggestive of pathologies in the central auditory system, the impact of blast exposure on central auditory processing remains poorly understood. Here we examined the effects of blast shockwaves on acoustic response properties and the tonotopic frequency map in the auditory cortex. We found that multiunits recorded from the auditory cortex exhibited higher acoustic thresholds and broader frequency tuning in blast-exposed animals. Furthermore, the frequency map in the primary auditory cortex was distorted. These changes may contribute to central auditory processing disorders.
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Texto completo:
1
Base de dados:
MEDLINE
Assunto principal:
Córtex Auditivo
/
Percepção Auditiva
/
Traumatismos por Explosões
Limite:
Animals
Idioma:
En
Revista:
Neuroscience
Ano de publicação:
2018
Tipo de documento:
Article
País de afiliação:
Estados Unidos