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Dimerization of the cellular prion protein inhibits propagation of scrapie prions.
Engelke, Anna D; Gonsberg, Anika; Thapa, Simrika; Jung, Sebastian; Ulbrich, Sarah; Seidel, Ralf; Basu, Shaon; Multhaup, Gerd; Baier, Michael; Engelhard, Martin; Schätzl, Hermann M; Winklhofer, Konstanze F; Tatzelt, Jörg.
Afiliação
  • Engelke AD; Department of Biochemistry of Neurodegenerative Diseases, Ruhr University Bochum, D-44801 Bochum, Germany.
  • Gonsberg A; Department of Biochemistry of Neurodegenerative Diseases, Ruhr University Bochum, D-44801 Bochum, Germany.
  • Thapa S; Department of Comparative Biology and Experimental Medicine, Faculty of Veterinary Medicine, and Calgary Prion Research Unit, University of Calgary, Calgary, Alberta T2N 4Z6, Canada.
  • Jung S; Department of Biochemistry of Neurodegenerative Diseases, Ruhr University Bochum, D-44801 Bochum, Germany.
  • Ulbrich S; Department of Biochemistry of Neurodegenerative Diseases, Ruhr University Bochum, D-44801 Bochum, Germany.
  • Seidel R; Department of Structural Biochemistry, Max Planck Institute of Molecular Physiology, D-44227 Dortmund, Germany.
  • Basu S; Department of Pharmacology and Therapeutics, McGill University, Montreal H3G 1Y6, Canada.
  • Multhaup G; Department of Pharmacology and Therapeutics, McGill University, Montreal H3G 1Y6, Canada.
  • Baier M; Research Group Proteinopathies/Neurodegenerative Diseases, Centre for Biological Threats and Special Pathogens (ZBS6), Robert Koch-Institut, D-13353 Berlin, Germany.
  • Engelhard M; Department of Structural Biochemistry, Max Planck Institute of Molecular Physiology, D-44227 Dortmund, Germany.
  • Schätzl HM; Department of Comparative Biology and Experimental Medicine, Faculty of Veterinary Medicine, and Calgary Prion Research Unit, University of Calgary, Calgary, Alberta T2N 4Z6, Canada.
  • Winklhofer KF; Department of Molecular Cell Biology, Institute of Biochemistry and Pathobiochemistry, Ruhr University Bochum, D-44801 Bochum, Germany.
  • Tatzelt J; Department of Biochemistry of Neurodegenerative Diseases, Ruhr University Bochum, D-44801 Bochum, Germany. Electronic address: Joerg.Tatzelt@rub.de.
J Biol Chem ; 293(21): 8020-8031, 2018 05 25.
Article em En | MEDLINE | ID: mdl-29636413

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Scrapie / Multimerização Proteica / Proteínas Priônicas / Neuroblastoma Limite: Animals / Humans Idioma: En Revista: J Biol Chem Ano de publicação: 2018 Tipo de documento: Article País de afiliação: Alemanha

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Scrapie / Multimerização Proteica / Proteínas Priônicas / Neuroblastoma Limite: Animals / Humans Idioma: En Revista: J Biol Chem Ano de publicação: 2018 Tipo de documento: Article País de afiliação: Alemanha