WDR1-regulated actin dynamics is required for outflow tract and right ventricle development.

Hu, Jisheng; Shi, Yingchao; Xia, Meng; Liu, Zhongying; Zhang, Ruirui; Luo, Hongmei; Zhang, Tongcun; Yang, Zhongzhou; Yuan, Baiyin

Hu, Jisheng; Shi, Yingchao; Xia, Meng; Liu, Zhongying; Zhang, Ruirui; Luo, Hongmei; Zhang, Tongcun; Yang, Zhongzhou; Yuan, Baiyin.

Afiliação

Hu J; Biomedical Research Institute, College of Life Science and Health, Wuhan University of Science and Technology, Wuhan, Hubei Province 430065, China.
Shi Y; MOE Key Laboratory of Model Animal for Disease Study, Model Animal Research Center, Nanjing Biomedical Research Institute, Nanjing University, Nanjing 210061, China.
Xia M; MOE Key Laboratory of Model Animal for Disease Study, Model Animal Research Center, Nanjing Biomedical Research Institute, Nanjing University, Nanjing 210061, China.
Liu Z; Biomedical Research Institute, College of Life Science and Health, Wuhan University of Science and Technology, Wuhan, Hubei Province 430065, China.
Zhang R; Biomedical Research Institute, College of Life Science and Health, Wuhan University of Science and Technology, Wuhan, Hubei Province 430065, China.
Luo H; MOE Key Laboratory of Model Animal for Disease Study, Model Animal Research Center, Nanjing Biomedical Research Institute, Nanjing University, Nanjing 210061, China.
Zhang T; Biomedical Research Institute, College of Life Science and Health, Wuhan University of Science and Technology, Wuhan, Hubei Province 430065, China.
Yang Z; MOE Key Laboratory of Model Animal for Disease Study, Model Animal Research Center, Nanjing Biomedical Research Institute, Nanjing University, Nanjing 210061, China. Electronic address: zhongzhouyang@nju.edu.cn.
Yuan B; Biomedical Research Institute, College of Life Science and Health, Wuhan University of Science and Technology, Wuhan, Hubei Province 430065, China. Electronic address: yuanby@wust.edu.cn.

Dev Biol ; 438(2): 124-137, 2018 06 15.

Article em En | MEDLINE | ID: mdl-29654745

Assuntos

Ventrículos do Coração/embriologia; Proteínas dos Microfilamentos/fisiologia; Actinas/genética; Actinas/metabolismo; Animais; Embrião de Mamíferos/embriologia; Desenvolvimento Embrionário/genética; Desenvolvimento Embrionário/fisiologia; Regulação da Expressão Gênica no Desenvolvimento/genética; Coração/embriologia; Cardiopatias Congênitas/genética; Camundongos; Camundongos Knockout; Proteínas dos Microfilamentos/genética; Proteínas dos Microfilamentos/metabolismo; Miocárdio; Miócitos Cardíacos; Organogênese; Transdução de Sinais; Obstrução do Fluxo Ventricular Externo

Palavras-chave

Actin; Mouse; Second heart field; WDR1

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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Ventrículos do Coração / Proteínas dos Microfilamentos Limite: Animals Idioma: En Revista: Dev Biol Ano de publicação: 2018 Tipo de documento: Article País de afiliação: China

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